摘要
目的分析地塞米松分别同卡贝缩宫素与卡前列素氨丁三醇联合用于防治高危妊娠的产妇产后出血的临床效果。方法选取2015年2月至2017年2月于我院就诊的高危妊娠产妇100例,随机分为研究组与对照组。研究组产妇应用卡贝缩宫素联合地塞米松治疗,对照组应用卡前列素氨丁三醇联合地塞米松治疗。比较两组产妇的出血预防效果、心率、血压、产后出血率、出血量、治疗费用及不良反应发生情况。结果研究组产妇的出血预防总有效率明显高于对照组(P<0.05);治疗后30 min,两组产妇的心率、舒张压和对照组的收缩压均明显增加(P<0.05),但组间比较差异不显著(P>0.05);研究组产妇24 h内的出血率、出血量、治疗费用和不良反应总发生率均明显优于对照组(P<0.05)。结论地塞米松同卡贝缩宫素联合用于高危妊娠产妇产后出血的防治作用显著,不良反应较少,治疗费用较低,值得临床推广。
Objective To analyze the clinical preventive efficacy of carbetocin and carboprost tromethamine combined with dexamethasone on postpartum hemorrhage in high-risk pregnancy puerperant. Methods A total of 100 cases of high-risk pregnant women from February 2015 to February 2017 in our hospital were selected and randomly divided into study group and control group. The study group was treated with carbetocin combined with dexamethasone, and the control group was given carboprost tromethamine combined with dexamethasone. The preventive efficacy of postpartum hemorrhage, heart rate,blood pressure, the rate of postpartum hemorrhage, blood loss volume, treatment cost and incidence of adverse reactions were compared between the two groups. Results The total effective rate of postpartum hemorrhage preventive efficacy in the study group was obviously higher than that in the control group（P〈0.05）. At 30 min after treatment, the heart rate, diastolic pressure in the two groups and the systolic pressure in the control group significantly increased（P〈0.05）, but there were no obvious differences in those between the two groups（P〉0.05）. The rate of postpartum hemorrhage in 24 h, blood loss volume,treatment cost and the total incidence of adverse reactions in the study group were obviously better than those in the control group（P〈0.05）. Conclusion Carbetocin combined with dexamethasone on postpartum hemorrhage in high-risk pregnancy puerperant has significant effect, it has less adverse reactions and low treatment cost, which is worthy of promotion.
出处
《临床医学研究与实践》
2017年第33期135-136,共2页
Clinical Research and Practice
关键词
卡前列素氨丁三醇
卡贝缩宫素
高危妊娠
产后出血
carboprost tromethamine
carbetocin
high-risk pregnancy
postpartum hemorrhage
