摘要
目的:了解我院儿科住院患儿的超说明书用药情况,为规范儿童超说明书用药、促进儿童安全合理用药提供参考。方法:利用电子病历系统从我院2016年12月至2017年2月1 279份儿科住院病历中抽取104份(8.13%),收集患儿的基本信息,审核病历中的用药医嘱,依据药品说明书及药学知识判断是否超说明书用药,并对超说明书用药类型等情况进行统计分析。结果:104份病历共包含用药医嘱1 739条,涉及18类81种药品,其中超说明书用药医嘱412条(23.69%),涉及药品类别主要为抗病毒药、维生素和矿物质、呼吸系统用药;超说明书用药类型前3位依次为超剂量(33.98%)、超适应人群(25.24%)、超适应年龄(19.42%)。结论:我院儿科住院医嘱存在超说明书用药情况,应逐步完善说明书儿童用药信息,加强超说明书用药的监管,以促进儿童安全合理用药。
Objective： To understand the off-label drug use in the pediatric inpatient cases in our hospital, promote children＇ medication safety and provide the basis for normalizing the off-label drug use. Methods： One hundred and four inpatient cases （8.13%） were randomly selected in the pediatric inpatients from December 2016 to February 2017. The children＇ s basic information was retrieved from the electronic medical records system. The admission notes were referred to and the medication orders were reviewed in order to determine whether off-label drug use based on drug instructions and pharmaceutical knowledge. The type and quantity of off- label drug use were statistically analyzed. Results： One hundred and four inpatient cases included 1,739 medical orders and involved 18 categories and 81 kinds of drugs. There were 412 off-label drug use orders （23.69%）. In the off-label drug use, antiviral drugs, vitamins and mineral substance and respiratory drugs were mostly. The proportions of the overdosage, the superfit population, and superfit age of administration were the top 3 （33.98% , 25.24% and 19.42% ）. Conclusion： There are off-label drug uses in pediatric inpatient medical orders. We shall gradually improve the instructions for children＇ s medication information, strengthen the supervision and management of the use of drugs and promote safe and rational use of drugs in pediatrics.
出处
《儿科药学杂志》
CAS
2017年第12期42-46,共5页
Journal of Pediatric Pharmacy
关键词
超说明书用药
儿科
住院
医嘱
合理用药
off-label drug use
pediatric
inpatient
medical order
rational use of drugs
