摘要
目的检测及分析过敏性疾病患者血清特异过敏原(sIgE)及总IgE水平,为临床诊疗提供依据。方法采用德国欧蒙印迹过敏原检测系统对1304名过敏性疾病患者进行20种特异性过敏原IgE及血清总IgE检测。结果过敏性疾病患者血清中总IgE阳性率受多种因素(性别、民族、年龄、疾病类型)的影响(P<0.05),1304例特异性过敏原阳性患者血清总IgE阳性率72.01%,不同过敏原在过敏性疾病患者群体中阳性率随着性别、民族、年龄以及疾病类型等因素的改变而表现出差异性变化(P<0.05),不同年龄以及不同过敏性疾病患者的主要过敏物质会发生改变(P<0.05)。结论对血清总IgE水平的测定是评估过敏性疾病及过敏性体质的重要指标,但同时不可忽视对血清总IgE阴性过敏性疾病患者的过敏原筛查。结合年龄与过敏性疾病类型开展有针对性的过敏原检测对筛查患者过敏原是有必要的。
Objective To investigate and analyze serum total IgE levels and the main types of allergens in 1304 patients with allergic dieases in Xinjiang. Methods Total 1304 patients with allergic dieases were recruited from January 2016 to December 2016. Twenty kinds of serum specific-IgE and total IgE were detected by EUROBlot Master system.Results The level of total IgE positive rates in patients with allergic disease was 72.01% which can be influenced by a variety of factors（gender, ethnicity, age, disease type）. The distribution of allergens in patients with allergic diseases changes significantly among many factors, such as, gender, ethnicity, age and disease type（P0.05= Age and type of disease is the most important factor. As these factors change, the main allergens can change.Conclusion Through the determination of serum total IgE level assessment of allergic diseases and an important indicator of allergic constitution, but measured by specific allergens in patients with negative result level of total IgE is not something that should be ignored. It is necessary to detection of allergens considering combining with age and symptoms factors.
出处
《新疆医学》
2017年第11期1233-1236,共4页
Xinjiang Medical Journal
