摘要
[目的]分析2014年浙江省肿瘤登记地区恶性肿瘤发病与死亡情况。[方法]收集浙江省14个肿瘤登记处上报的2014年恶性肿瘤发病、死亡及人口资料,对数据进行审核和汇总。计算恶性肿瘤发病和死亡的粗率、标化率、累积率（0~74岁）和前10位恶性肿瘤构成,并按地区（城市/农村）、性别和年龄进行分层分析。采用2000年全国普查人口年龄构成和Segi’s世界人口年龄构成作为标准人口,计算年龄标化发病和死亡率（中标率和世标率）。[结果]2014年,浙江省14个肿瘤登记处上报数据均符合标准,质量评价指标分别为：病理诊断比例（MV%）73.48%,只有死亡医学证明书比例（DCO%）1.14%,死亡/发病比0.53。肿瘤登记数据覆盖登记人口13 991 579人（城市9 328 970人,农村4 662 609人）,共报告恶性肿瘤新发病例49 644例,死亡病例26 459例。恶性肿瘤发病粗率为354.81/10万,中标率为215.55/10万,世标率为206.79/10万,累积率（0~74岁）为23.37%。男性发病率高于女性,城市发病率高于农村。恶性肿瘤发病率在40岁以后快速上升,在80~84岁年龄组达到高峰。恶性肿瘤死亡粗率为189.11/10万,中标率为99.19/10万,世标率为98.01/10万,累积率（0~74岁）为10.87%。男性死亡率高于女性,农村死亡率高于城市。恶性肿瘤死亡率在45岁以后快速上升,在85＋岁年龄组达到高峰。发病前10位的恶性肿瘤依次为肺癌、女性乳腺癌、甲状腺癌、结直肠癌、胃癌、肝癌、前列腺癌、宫颈癌、食管癌和子宫体癌,占全部恶性肿瘤发病的76.22%。死亡前10位的恶性肿瘤依次为肺癌、肝癌、胃癌、结直肠癌、食管癌、胰腺癌、女性乳腺癌、前列腺癌、淋巴瘤和脑肿瘤,前10位恶性肿瘤占全部恶性肿瘤死亡的83.63%。[结论]肺癌、消化系统恶性肿瘤和女性乳腺癌是威胁我省居民健康的主要恶性肿瘤,甲状腺癌发病增速较快,过度诊断、过度治疗不容忽视。
[Purpose] To analyze the cancer incidence and mortality in Zhejiang cancer registration areas in 2014.[Methods]Registration data from 14 local cancer registries of Zhejiang province in 2014 were collected and data quality were evaluated according to the criteria of quality control.The crude rates,age-standardized rates,cumulative rates and the proportion of top 10 cancers were calculated.Incidence and mortality stratified by areas（urban/rural）,gender and age groups were also analyzed.The fifth Chinese population census in 2000 and Segi’s population were applied to the age-standardized rates.[Results] The data from 14 local cancer registries were qualified for Zhejiang cancer annual report in 2014.The morphology verified cases（MV%） accounted for 73.48% and 1.14% of cancer cases were identified through death certifications only（DCO%） with the mortality to incidence ratio（M/I） of 0.53.The coverage of population from the 14 local cancer registries were 13 991 579（9 328 970 in urban and 4 662 609 in rural）.There were 49 644 new cancer cases diagnosed and 26 459 cancer deaths reported in 2014.The crude cancer incidence in Zhejiang cancer registration areas was 354.81/105.Age-standardized incidence rates adjusted by Chinese standard population（ASIRC） and by world standard population（ASIRW） were 215.55/105 and 206.79/105,respectively.The cumulative incidence rate（0~74 years old） was 23.37%.Males had higher incidence than females,and the incidence in urban areas were higher than that in rural areas.Cancer incidence increased rapidly after the age of 40 and reached the peak at the age group of 80~84 years.The crude cancer mortality was 189.11/105.Age-standardized mortality rate adjusted by Chinese standard population（ASMRC） and by world standard population（ASMRW）were 99.19/105 and 98.01/105,respectively.The cumulative mortality rate（0 ~74 years old） was 10.87%.Males also had higher mortality than females,while the mortality in rural areas was higher than that in urban areas.Cancer mortality increased rapidly after the age of 45 and reached the peak at the age group of 85＋years.The top ten common cancer types were lung cancer,female breast cancer,thyroid cancer,colorectal cancer,stomach cancer,liver cancer,prostate cancer,cervical cancer,esophageal cancer and uterine cancer,accounting for 76.22% of all cancers.Lung cancer was the leading cause of cancer death,followed by liver cancer,gastric cancer,colorectal cancer,esophageal cancer,pancreas cancer,female breast cancer,prostate cancer,lymphoma and brain tumor.The mortality of the top ten cancers accounted for 83.63% of all cancer deaths.[Conclusion] Lung cancer,malignant tumor in the digestive system and female breast cancer are still the major cancer burden in Zhejiang.Thyroid cancer is increasing at an alarming rate,which may associated with the overdiagnosis and overtreatment.
出处
《中国肿瘤》
CAS
CSCD
北大核心
2018年第1期15-22,共8页
China Cancer
基金
浙江省自然科学基金(LY15H260001)
关键词
肿瘤登记
恶性肿瘤
发病率
死亡率
浙江
cancer registry
malignant tumor
incidence
mortality
Zhejiang
