摘要
膝骨关节炎(knee osteoarthritis,KOA)常见于中老年人,是以膝关节痛、肿胀、晨僵为主要特征的慢性退行性疾病,严重影响到患者的运动功能和身体健康。目前仍缺乏其早期诊断及治疗的方法。结合近年来KOA与炎性细胞因子相关性研究,探讨KOA与IL-1β、IL-6、TNF-α、TGF-β、IL-10、IL-17、IL-37等炎性因子的关系,为KOA的诊断和治疗提供理论依据。
Knee osteoarthritis（KOA）is a common chronic degenerative disease in the elderly population.It is characterized by knee-joint pain,swelling,morning stiffness and seriously affects the patients′motor function and physical health.So far,there is no early diagnosis and effective treatment for it.This paper outlined the recent researches on knee osteoarthritis and inflammatory cytokines to discuss the relationship between knee osteoarthritis and inflammatory factors such as IL-1β,IL-6,TNF-α,TGF-β,IL-10,IL-17 and IL-37,and provide the theoretical basis for the diagnosis and treatment of knee osteoarthritis.
作者
袁颖超
廖秋菊
YUAN Yingchao;LIAO Qiuju(Xuanwu Hospital of Capital Medical University , Beijing 100054 ,China)
出处
《药学实践杂志》
CAS
2018年第1期9-12,共4页
Journal of Pharmaceutical Practice
基金
首都医科大学本科生科研创新项目(XSKY2016112)
关键词
膝骨关节炎
炎性细胞因子
诊断
治疗
knee osteoarthritis
inflammatory cytokines
diagnosis
treatment
