摘要
目的:探讨100例失眠患者采用重复经颅磁刺激联合曲唑酮治疗的效果。方法:将2016年5月-2017年5月在我院神经内科治疗的100例失眠患者随机分为两组,对照组采用曲唑酮治疗,观察组采用重复经颅磁刺激联合曲唑酮治疗,比较两组患者的临床疗效、睡眠改善情况。结果:观察组治疗总有效率为94%,较对照组的76%有显著提高,差异有统计学意义(P<0.05);观察组治疗后PSQI评分明显低于对照组,差异有统计学意义(P<0.05);观察组治疗后HAMA、HAMD评分明显较对照组改善,差异有统计学意义(P<0.05)。结论:采用重复经颅磁刺激联合曲唑酮治疗失眠效果显著,能有效提高睡眠质量,改善焦虑抑郁情绪对睡眠的影响,具有积极的临床意义。
Objectives: To explore the effect of repeated transcranial magnetic stimulation with trazodone on treating 100 cases of insomnia. Methods: 100 cases of insomnia treated in neurology department of our hospital from May 2016 to May 2017 were selected and randomly divided into two groups, the control group received trazodone and the observation group received repeated transcranial magnetic stimulation with trazodone. The clinical effect and improvement of the sleep of two groups were compared. Results: The total effective rate in the observation group was 94%, which was significantly higher than 76% in the control group, the difference was statistically significant, P<0.05. After treatment, the score of PSQI in the observation group was significantly lower than that in the control group, and the difference was statistically significant, P<0.05. After treatment, the score of HAMA and HAMD in the observation group was more significantly improved than that in the control group, the difference was statistically significant, P<0.05. Conclusion: Repeated transcranial magnetic stimulation with trazodone had significant effect in treating insomnia. It could effectively improve the quality of sleep, relieve the effect of anxiety and depression on sleep, with a positive clinical significance.
出处
《中医临床研究》
2017年第36期133-135,共3页
Clinical Journal Of Chinese Medicine
关键词
失眠
重复经颅磁刺激
曲唑酮
治疗效果
Insomnia
Repetitive transcranial magnetic stimulation
Trazodone
Therapeutic effects