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心肌型脂肪酸结合蛋白在急性心肌梗死早期诊断中的价值 被引量:2

Clinical Research of H-FABP in Early Diagnosis of Patients With Acute Myocardial Infarction(AMI)
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摘要 目的观察心型脂肪酸结合蛋白(H-FABP)诊断早期急性心肌梗死(AMI)的效果。方法选择我院收治的150例AMI患者为观察组,并选择同期150例健康体检者为对照组。两组均测定H-FABP、心肌肌钙蛋白I(c Tn I)以及肌酸激酶同工酶(CK-MB)水平。结果观察组胸痛发作不同时间段内H-FABP水平均高于对照组(P<0.05);观察组内H-FABP诊断敏感性、特异性等指标优于c Tn I、CK-MB(P<0.05)。结论 H-FABP检测早期AMI准确度高。 Objective To observe the effect of H-FABP in the diagnosis of early AMI. Methods 150 AMI patients were selected as observation group, and 150 healthy subjects were selected as control group. The levels of H-FABP, cardiac troponin I (cTnI) and creatine kinase isoenzyme (CK-MB) were measured between two groups. Results The level of H-FABP in different periods of chest pain of observation group was signifcantly higher than control group (P 〈 0.05). The sensitivity and negative predictive value of H-FABP in the observation group were significantly better than cTnI and CK-MB (P 〈 0.05). Conclusion H-FABP has high accuracy in early detection of AMI.
作者 邵春芳
出处 《中国卫生标准管理》 2018年第2期120-121,共2页 China Health Standard Management
关键词 心型脂肪酸结合蛋白 急性心肌梗死 早期诊断 H-FABP AMI early diagnosis
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