摘要
目的探讨上海市青浦区朱家角人民医院(以下简称"我院")社区获得性肺炎(CAP)患者抗菌药物应用情况,以提高抗菌药物的临床应用合理性。方法回顾性总结2016年1月~2017年6月我院住院病历中所有诊断为CAP的患者病史。按使用抗菌药物的种类、使用频率、联合用药、疗程、治疗结果等进行统计分析,以药物利用指数(DUI)作为药物使用的判断指标。结果我院治疗CAP的抗菌药物中,使用频次前3位的为头孢菌素类、氟喹诺酮类、青霉素类;使用最多的为头孢替安;均为二联用药,以头孢菌素类和氟喹诺酮类联合最为常见,最多的是头孢替安联合左氧氟沙星氯化钠[14例(33.33%)],疗程为(5.28±3.83)d;153例患者中痊愈50例(32.68%),好转98例(64.05%),未愈2例(1.31%),出院或转院3例(1.96%);DUI为0.9~1.1的有4种(26.67%),DUI<0.9的有3种(20.00%),DUI>1.1的有8种(53.33%)。结论我院CAP患者抗菌药物使用情况总体基本合理,但还存在一些不足,仍需进一步规范用药。
Objective To explore the application situations of antibacterial agents in patients with community-acquired pneumonia （CAP） in Zhujiajiao People＇s Hospital of Qingpu District in Shanghai City （＂our hospital＂ for short）, so as to improve the rationality of clinical application of antibacterial agents. Methods The medical history of patients diagnosed as CAP in all medical records Of our hospital from January 2016 to June 2017 was summarized retrospectively. The type of antibacterial agents, frequency, drug combination, course of treatment, therapeutic effect and so on were analyzed statistically, the drug utilization index （DUI） was used as judging indicator of drug use. Results Among the an- tibacterial agents of CAP treatment in our hospital, the top three of use frequency was cephalosporins, fluoroquinolones and penicillins, the most widely-used was Cefotiam, all was in double combinations, the most common was combination of cephalosporins and fluoroquinolones [14 cases （33.33%）], the course was （5.28±3.83） d. Among 153 cases of patients, 50 cases （32.68%） were cured, 98 cases （64.05%） were improved, 2 cases （1.31%） were not healed, 3 cases （1.96%） were discharged or transferred. There were 4 kinds （26.67%） of antibacterial agents with DUI ranged from 0.9 to 1.1, 3 kinds （20.00%） of antibacterial agents with DUI〈0.9, 8 kinds （53.33%） of antibacterial agents with DUI〉1.1. Conclusion The total application situations of antibacterial agents in patients with CAP in our hospital are basically reasonable, but there are still some disadvantages and the drug use still needs further standardized.
出处
《中国医药导报》
CAS
2018年第5期136-139,共4页
China Medical Herald
基金
国家自然科学基金青年科学基金项目(81703503)
关键词
社区获得性肺炎
抗菌药物
合理用药
Community-acquired pneumonia
Antibacterial agents
Rational drug use
