摘要
目的探讨血管介入栓塞术对颅内动脉瘤患者神经功能和生活质量的影响。方法选取2014年1月至2017年1月期间本院神经外科住院部颅内动脉瘤患者134例作为研究对象,根据血管介入栓塞术不同时机将患者分为两组,早期介入组(n=67)治疗时间距发病时间≤72小时,延期介入组(n=67)治疗时间距发病时间>72 h。参照神经功能缺损(NFI)量表、改良Rankin量表与MOS健康状况调查问卷(SF-36)标准分别评定神经功能、预后状况与生活质量。结果术后早期介入组完全栓塞率与预后良好率明显高于延期介入组,部分栓塞率与预后不良率明显低于延期介入组(P<0.05)。术前两组NFI评分与SF-36评分比较差异无统计学意义(P>0.05),术后3个月,全部患者NFI评分明显低于手术前,SF-36评分明显高于手术前,手术前后比较差异有统计学意义(P<0.05),其中早期介入组NFI评分明显低于延期介入组,SF-36评分明显高于延期介入组,两组比较差异有统计学意义(P<0.05)。结论早期血管介入栓塞术治疗颅内动脉瘤患者的疗效满意,有助于改善神经功能和预后状况,从而提升生活质量,值得临床推广应用。
Objective To study the influence of vascular interventional embolization for patients with intracranial aneurysm on neurologic function and life quality. Methods From Jan. 2014 to Jan. 2017,134 intracranial aneurysm cases from neurosurgery department of our hospital were recruited. According to the time interval from onset to interventional embolization, the patients were categoried into early interven-tional group(n=67, time interval≤72 h) and delayed interventional group(n=67, time interval> 72 h). The neurologic function, prognosis and life quality were assessed respectively by neurologic function impairment(NFI) scale, modified Rankin scale and the MOS 36-items short form-health survey(SF-36) standards. Results After intervention, the complete embolism rate and good prognosis rate of early interventional group were significantly higher than the delay interventional group, partial embolism rate and defective prognosis rate were significantly lower than the delay interventional group(P <0.05). The pre-intervention NFI score and SF-36 score between the two groups was not statistically significant different(P>0.05). Three months after intervention, NFI score of all patients was lower than pre-intervention, SF-36 score was significantly higher than pre-intervention(P<0.05). The NFI score of early interventional group was significantly lower than the delay interventional group, SF-36 score was significantly higher than the delay interventional group( P <0. 05). Conclusion The clinical outcome of early vascular interventional embolization of intracranial aneurysm is satisfying, which helps to improve neurologic function and prognosis, thus improve life quality,and is worthy of clinical popularization and application.
出处
《中国血管外科杂志（电子版）》
2017年第4期283-286,共4页
Chinese Journal of Vascular Surgery(Electronic Version)
关键词
血管介入栓塞术
颅内动脉瘤
神经功能
生活质量
Vascular interventional embolization
Intracranial aneurysm
Neurologic function
Quality of life
