摘要
目的探讨曲克芦丁脑蛋白水解物和脑苷肌肽治疗新生儿缺氧缺血性脑病的临床效果。方法选取2015年2月至2017年2月我院收治的缺氧缺血性脑病的270例患儿为研究对象,将所有患儿按不同治疗方法分为对照组与观察组,各135例。对照组患儿给予脑苷肌肽治疗,观察组患儿给予曲克芦丁脑蛋白水解物治疗。比较两组患儿的NBNA评分、不良反应发生率及临床效果。结果治疗后1、2周,两组患者的NBNA评分均明显高于治疗前,且观察组明显高于对照组(P<0.05);观察组不良反应总发生率明显低于对照组(P<0.05);观察组总有效率为96.30%,明显高于对照组的78.52%(P<0.05)。结论曲克芦丁脑蛋白水解物治疗新生儿缺氧缺血性脑病临床效果更优,值得临床推广应用。
Objective To investigate the clinical effects of troxerutin and cerebroprotein hydrolysate and cattle encephalon glycoside and ignotin on neonatal hypoxic ischemic encephalopathy. Methods Two hundred and seventy neonates with hypoxic ischemic encephalopathy admitted and treated in our hospital from February 2015 to February 2017 were included and divided into control group and observation group according to the different treatment methods, with 135 cases in each group.The control group was given cattle encephalon glycoside and ignotin, and the observation group was treated with troxerutin and cerebroprotein hydrolysate. The NBNA scores, adverse reactions and clinical effects were compared between the two groups. Results At 1 and 2 weeks after treatment, the NBNA scores of the two groups were higher than those before treatment,and those of the observation group were higher than the control group(P<0.05). The total incidence of adverse reactions of the observation group was lower than that of the control group(P<0.05). The total effective rate of the observation group was higher than that of the control group(P<0.05). Conclusion Troxerutin and cerebroprotein hydrolysate has better clinical effects on neonatal hypoxic ischemic encephalopathy, which is worthy of clinical application and promotion.
出处
《临床医学研究与实践》
2018年第7期83-84,共2页
Clinical Research and Practice
关键词
曲克芦丁脑蛋白水解物
脑苷肌肽
新生儿缺氧缺血性脑病
troxerutin and cerebroprotein hydrolysate
cattle encephalon glycoside and ignotin
neonatal hypoxic ischemic encephalopathy
