摘要
目的监测流感病毒在乌鲁木齐市儿童中的流行情况,为制定儿童流感防治策略提供科学依据。方法以2014-2016年门、急诊0~14岁组流感样病例患儿为监测对象,采集患儿咽拭子标本送至国家流感网络实验室,运用实时荧光PCR对流感病毒进行核酸检测和分型,并用统计软件对数据进行分析。结果 2014-2016年门、急诊共接诊0~14岁组患儿795 906例,其中流感样病例(Influenza-like illness,ILI)97 815例(12.29%),ILI%呈逐年增长趋势,不同年份ILI%差异有统计学意义(χ2=876.12,P<0.01);共采集流感样病例咽拭子标本4 562份,检出流感病毒阳性1 014份(22.23%),其中5~14岁组儿童519例,明显高于0~4岁组,差异有统计学意义(χ2=55.62,P<0.01)。乌鲁木齐市儿童流感流行于冬春季节,新甲型H1N1、乙型和甲型H3N2流感病毒交替流行。结论乌鲁木齐市儿童中甲型、乙型流感病毒交替流行,不同年份的优势流行株不同,学龄儿童为主要易感儿童,应当加强监测。
Objective Monitoring of influenza virus prevalence among children in Urumqi,and to provide scientific evidence for the prevention of influenza in children. Methods With the 2014-2016 influenza sentinel hospitals outpatient,emergency 0 ~14 years of influenza like cases were collected as the monitoring object,children with throat swab samples were sent to the national influenza network laboratory,using real time PCR of influenza virus nucleic acid detection and typing,and the data were analyzed with statistical software. Results There were 795 906 cases of 0 ~ 14 years old children,including 97 815（ 12. 29%）influenza-like illness（ ILI） from 2014 to 2016,the ILI% showed a yearly increasing trend,and the difference of ILI% in different years was statistically significant（ χ2= 876. 12,P〈0. 001）; 4 562 samples of pharyngeal swabs from children with influenza-like cases were collected,the influenza virus positive 1 014（ 22. 23%） was detected,among them,519 cases of children aged 5 ~ 14 years,was significantly higher than that in the 0 ~ 4 age group,the difference was statistically significant（ χ2= 55. 62,P〈0. 001）. Urumqi city in the spring and winter flu epidemic in children,visible H1 N1 flu virus,alternating epidemic influenza B and H3 N2 influenza virus. Conclusion Alternating prevalence of influenza A and B virus in Urumqi children,and the dominant epidemic strains in different years,and school-age children as the main child,should be monitored.
作者
蒲玉娇
樊旭成
薛娜
高枫
韩志国
相然
芮宝玲
PU Yujiao, FAN Xucheng, XUE Na, GAO Feng, HAN Zhiguo, XIANG Ran, RUI Baoling(Department of Epidemiology and Statistics, School of Public Health, Xinjiang Medical University, Urumqi 830011, Chin)
出处
《医学动物防制》
2018年第4期338-341,共4页
Journal of Medical Pest Control
基金
新疆维吾尔自治区自然科学基金资助项目(2014211A020)
