摘要
为了明确苦参碱金属配合物的抑菌活性,于无水乙醇中合成2种配合物,采用元素分析、红外光谱分析、差热热重同步分析、单晶衍射分析对配合物的结构进行表征,确定组成及结构。采用菌丝生长速率法测定配体及配合物对番茄灰霉病菌、小麦赤霉病菌、马铃薯晚疫病菌的抑菌活性。结果表明,合成的配合物经结构表征后,确定其结构为1分子苦参碱与1分子金属离子配位。药剂质量浓度为800mg/L时,苦参碱金属配合物的抑菌活性均高于配体,尤其锌配合物对番茄灰霉病菌的抑制率提高近7.1倍,铁配合物对小麦赤霉病菌以及锌配合物对马铃薯晚疫病菌的抑菌活性最强,其抑制率分别为79.8%、95.2%。苦参碱能与铁、锌金属离子形成金属配合物,且配合物的抑菌活性相对于配体有不同程度的提高。
Matrine-Fe and matrine-Zn complexes were synthesized in absolute alcohol and elemental analysis, IR spectrum, TG, and X-ray single-crystal diffraction were used to represent the structure foridentifying the composition and construction. Their antifungal activity against Botrytis cinerea ,Fu- sarium grarninearum, Phytophthorain festans were investigated by using mycelium growth rata meth- od in the laboratory. Through the structural representation, the metal complex structure was con- firmed to include one matrine molecule and one metallic ion. The results of antifungal activity investi- gation showed that inhibiting capacity on funguses of metal complexes were better than ligand, espe- cially for Botrytis cinerea ,the matrine-Zn inhibition rate increased 7.1 times than martine in concen- tration of 800 mg/L. Matrine-Fe showed the strongest inhibiting capacity on Fusarium graminearum and Matrine-Zn（ 11 ）had strongest inhibiting capacity on Phytophthorain festans with antifungal inhi- bition rate of 79.8%, 95. 2% respectively. Matrine could form metal complexes with iron and zinc ions. After matrine and metallic ionformed metal complex, the inhibiting capacity were enhanced.
作者
刘涵
李海
王永宏
刘存寿
张兴
LIU Han1 ,LI Hai1 , WANG Yonghong1, 2, LIU Cunshou1＇3 and ZHANG Xing1＇2(1. Reseach and Development Center of Biorational Pesticide,Northwest A＆F University,Yangling Shaanxi 712100,China 2. Reseach Center o[ Biopesticied Technology~Engineering,Yangling Shananxi 712100,China; 3. College of Natural Resources and Environment,Northwest A~F University ,Yangling Shaanxi 712100,Chin)
出处
《西北农业学报》
CAS
CSCD
北大核心
2018年第3期432-439,共8页
Acta Agriculturae Boreali-occidentalis Sinica
基金
国家科技支撑计划(2014BAD23B01)
杨凌示范区产学研用协同创新重大专项(2016CXY-13)~~
