摘要
目的探究果胶铋与阿莫西林合用治疗慢性萎缩性胃炎的临床效果。方法选取2017年5月15日~2017年12月20日一五七医院内科收治的96例慢性萎缩性胃炎患者作为研究对象,按照随机数字表法将其分为两组,每组各48例。观察组患者给予果胶铋联合阿莫西林进行治疗,对照组患者给予克拉霉素联合果胶铋进行治疗。比较两组患者的临床治疗总有效率及药物不良反应(头晕、皮疹、恶心)发生率。结果观察组患者的治疗总有效率(95.83%)高于对照组(72.92%),差异有统计学意义(P<0.05)。观察组患者的药物不良反应发生率(4.17%)低于对照组(20.83%),差异有统计学意义(P<0.05)。结论果胶铋联合阿莫西林用于治疗慢性萎缩性胃炎具有极高的临床价值,能够缓解临床症状,值得应用及推广。
Objective To explore the clinical effect of Colloidal Bismuth Pectin combined with Amoxicillin in the treatment of chronic atrophic gastritis.Methods A total of 96 patients with chronic atrophic gastritis admitted to our hospital from May 15,2017 to December 20,2017 were selected as the study subjects.The patients were divided into two groups by a random number table method,with 48 patients in each group.Patients in observation group were treated with Colloidal Bismuth Pectin combined with Amoxicillin,while in control group,they were treated with Clarithromycin and Colloidal Bismuth Pectin.The total clinical effectiveness rate and incidence of adverse drug reactions such as dizziness,rash,and nausea were compared between the two groups.Results The total effectiveness rate in the observation group was 95.83%,which was higher than that of the control group accounting for 72.92% with statistical significance(P〈0.05).The incidence of adverse drug reactions was 4.17%,which was lower than that in the control group accounting for20.83% with a significant difference(P〈0.05).Conclusion The combination of Colloidal Bismuth Pectin and Amoxicillin in the treatment of chronic atrophic gastritis is of high clinical value.It can relieve clinical symptoms,which is worthy of application and promotion.
作者
张明秋
ZHANG Ming-qiu(Department of Internal Medicine,157thHospital,Liaoning Province,Shenyang 110045,China)
出处
《中国当代医药》
2018年第12期101-103,共3页
China Modern Medicine
关键词
果胶铋
阿莫西林
慢性萎缩性胃炎
临床效果
Colloidal Bismuth Pectin
Amoxicillin
Chronic atrophic gastritis
Clinical effect