摘要
目的:探讨头孢曲松钠与苄星青霉素联合应用于快速血浆反应素(RPR)高滴度妊娠合并梅毒患者中的效果。方法:选择2014年5月~2016年5月某院收治的RPR高滴度(>1∶16)的妊娠合并梅毒患者94例,以随机数字表将其分为对照组(采用苄星青霉素治疗)与研究组(在对照组的基础上采用头孢曲松钠治疗)各47例,对比两组临床疗效与妊娠结局。结果:两组治疗的总有效率对比中,研究组93.62%高于对照组76.60%(P<0.05);研究组不良妊娠结局的发生率2.13%与对照组4.26%对比无明显差异(P>0.05)。结论:RPR高滴度妊娠合并梅毒患者采用头孢曲松钠与苄星青霉素联合治疗效果确切,安全性佳。
Objective：To investigate the effect of ceftriaxone sodium and benzylpenicillin in the treatment of RPR high titer pregnancy with syphilis.Methods：From May 2014 to May 2016,94 patients with RPR high titer（more than 1∶16）pregnancy with syphilis treated in a hospital were selected and randomly divided into control group（treated with benzylpenicillin therapy）and study group（treated with ceftriaxone sodium on the basis of the control group）,with 47 cases in each group.The clinical efficacy and pregnancy outcome were compared between the two groups.Results：The total effective rate of the study group was 93.62%,which was higher than that of the control group（76.60%）（P〈0.05）.There was no significant difference in the incidence of adverse pregnancy outcomes between the study group（2.13%）and the control group（4.26%）（P〉0.05）.Conclusion：Ceftriaxone sodium and benzylpenicillin in the treatment of RPR high titer pregnancy with syphilis has exact effect and good safety.
作者
李爱玲
Li Ailing(Department of Obstetrics and Gynecology ,Zhengzhou No.6 People＇s Hospital ,Zhengzhou 45000)
出处
《数理医药学杂志》
2018年第5期743-744,共2页
Journal of Mathematical Medicine
