摘要
腹泻是小儿临床常见症状,肠道微生态失调是腹泻的主要因素,七味白术散对小儿腹泻治愈效果显著.肠道微生态是目前研究的热点,对中药疗效及疾病形成机理的阐明具有重要意义.根据微生态的内涵,通过检索文献,本文对七味白术散影响肠道微生物群落结构、肠道酶活性及肠道微生物代谢等方面的研究进展进行综述,阐述七味白术散在肠道黏膜屏障的基础下,促进肠道益生菌的生长,抑制有害菌的繁殖,调整肠道菌群,提高肠道酶活性,从而达到治愈效果.七味白术散可以在酶活性水平及酶产生菌水平对肠道乳糖酶进行调节.这些可以为七味白术散治疗腹泻机理的揭示,促进七味白术散的临床应用提供依据.
Diarrhea is a common clinical symptom in children.The main factor responsible for diarrhea is intestinal microecological imbalance. The effect of Qiwei Baizhu powder on infantile diarrhea is remarkable. Intestinal microecology is the hot topic in current research. It is of great significance to elucidate the curative effect of Chinese medicine and the pathogenesis of diarrhea. According to the connotation of microecology and by searching the literature, this article reviews the progress in research of intestinal microbial community structure, intestinal enzyme activity, and intestinal microbial metabolism. It is shown that Qiwei Baizhu powder can repair the intestinal mucosal barrier, inhibit the propagation of harmful bacteria in the intestine, adjust intestinal flora, and improve intestinal enzyme activity by promoting the growth of beneficial bacteria in the gut, especially the activity of intestinal lactase. Qiwei Baizhu powder can regulate the levels of enzyme activity and production. These results can be used to reveal the mechanism of diarrhea to promote the clinical application of Qiwei Baizhu powder.
作者
刘娅薇
惠华英
谭周进
Ya-Wei Liu;Hua-Ying Hui;Zhou-Jin Tan(Department of Microbiology, Hu＇nan University of Chinese Medicine, Changsha 410208, Hu＇nan province, China)
出处
《世界华人消化杂志》
CAS
2018年第17期1022-1028,共7页
World Chinese Journal of Digestology
基金
长沙市科技局项目
No.kq1706057~~
关键词
七味白术散
肠道乳糖酶
肠道微生态
肠道酶活性
微生物代谢
Qiwei Baizhu powder
Intestinal lactase
Intestinal microecology
Intestinal enzyme activity
Microbial metabolism
