摘要
目的分析深圳市罗湖区300例15~44岁男性吸烟指数(SI)与颈动脉内膜中层厚度(IMT)的相关性。方法将2016年7月~2017年11月深圳市罗湖区15~44岁的300例吸烟男性纳入研究组,将同期300名同年龄段的不吸烟男性纳入对照组。行健康状况问卷调查和体检,分析SI与颈动脉IMT的相关性。结果研究组双侧颈动脉IMT、颈动脉僵硬度系数、PSV/EDV、PI均高于对照组,且左侧高于右侧(P<0.05);研究组双侧颈动脉CC、DC均低于对照组,且左侧低于右侧(P<0.05);研究组双侧颈动脉RI比较,差异无统计学意义(P>0.05);对照组双侧颈动脉IMT、颈动脉弹性参数、颈动脉血流动力学指标比较,差异无统计学意义(P>0.05);SI与双侧颈动脉IMT均成显著正相关(P<0.05)。结论吸烟可引起双侧颈动脉IMT增厚、降低颈动脉弹性和血流速度,且随着SI升高,吸烟者双侧颈动脉IMT增厚程度越显著。
Objective To analyze the correlation between smoking index（SI） and carotid artery intima-media thickness（IMT） in 300 male patients aged from 15 to 44 years old in Luohu District of Shenzhen. Methods A total of 300 male smokers aged from 15 to 44 years old in Luohu District of Shenzhen from July 2016 to November 2017 were included in the study group, and 300 non-smoking men of the same age were included in the control group. The health survey and physical examination were made, and the correlation between SI and carotid artery IMT was analyzed. Results The levels of bilateral carotid artery IMT, carotid artery stiffness index, PSV/EDV and PI in the study group were higher than those in the control group, and the levels in the left side were higher than those in the right side（P〈0.05）. The levels of bilateral carotid artery CC and DC in the study group were lower than those in the control group, and the levels in the left side were lower than those in the right side（P〈0.05）. There was no significant difference in the bilateral carotid artery RI in the study group（P〈0.05）. There was no significant difference in the bilateral carotid artery IMT, carotid artery elasticity parameters and carotid hemodynamics indexes between bilateral in the control group（P〉0.05）. There was a significant positive correlation between SI and bilateral carotid artery IMT（P 〈0.05）. Conclusion Smoking can cause the thickening of bilateral carotid IMT and the decrease of carotid artery elasticity and blood flow velocity. With the increase of SI, the IMT thickening of bilateral carotid artery is more significant.
作者
黄科军
刘婷
郝晋忠
游敏玲
魏东
HUANG Ke-jun;LIU Ting;HAO Jin-zhong;YOU Min-ling;WEI Dong(Traditional Chinese Medicine Hospital of Luohu District,Shenzhen City,Guangdong Province,Shenzhen 518000,China)
出处
《中国当代医药》
2018年第20期150-152,166,共4页
China Modern Medicine
基金
广东省深圳市罗湖区软科学研究计划项目(罗科[2016]37号文件第25号)
关键词
15~44岁男性
吸烟指数
颈动脉内膜中层厚度
弹性参数
血流动力学
Males aged from 15 to 44 years old
Smoking index
Carotid artery intima-media thickness
Elasticityparameters
Hemodynamics
