摘要
目的:观察脉管通胶囊联合西药治疗颈动脉粥样硬化斑块的临床疗效。方法:选取120例颈动脉粥样硬化斑块患者随机分为治疗组60例与对照组60例,对照组口服辛伐他汀,治疗组在对照组基础上加服脉管通胶囊;两组均治疗3个月后观察临床疗效,治疗前后分别检测两组患者颈动脉内膜中层厚度(IMT)、血脂变化。结果:治疗后两组颈动脉内膜中层厚度(IMT)变薄、颈动脉粥样硬化斑块临床疗效和血清TC、TG、HDL-C、LDL-C较治疗前有明显好转,两组治疗前后比较差异有统计学意义(P<0.05)。治疗组在治疗后颈动脉内膜中层厚度(IMT)较对照组变薄、颈动脉粥样硬化斑块面积较对照组缩小,血清TC、TG、LDL-C均较对照组改善明显,两组比较差异有统计学意义(P<0.05)。结论:脉管通胶囊联合辛伐他汀可显著增加抗动脉粥样硬化的效果,使粥样硬化斑块减小,降低颈动脉内膜中层厚度,调节血脂水平,值得临床推广应用。
Objective： To observe the clinical effect of Mai Guan Tong Capsule on patients with carotid atherosclerosis. Methods： 120 patients with carotid atherosclerosis were randonfiy divided into the treatment Group （60cases） and the control group （60cases）. The controlled group was given by simvastatin, the treatment group was given Mai Guan Tong Capsule on the basis of the controlled group. The Intima-media- thickness （IMT）, TC, TG, HDL- C, LDL- C and clinical syndrome of the patients of two groups before and after treatment were measured. Results ： After treatment, IMT was thinning of the two groups, and the serum TC, TG, HDL - C, LDL - C and clinical syndrome were better than that before the treatment, the effect of the two groups before and after treatment had significant difference （P 〈0. 05） . comparing the two groups after treatment, IMT of the treatment group was thinner than that of the controlled group, and the serum TC, TG, LDL - C and clinical syndrome of the treatment group were better than those of the controlled group, there were significant differences between the two groups （P 〈 0. 05）. Conclusion： Mai Guan Tong Capsule plays an important role in antiarrhythinia, which could better improve atherosclerosis in combination with simvastatin, Promoting plaque regression, reducing carotid intima -media thickness and Regulating blood lipid levels. Mai Guan Tong Capsule should be worthy of clinical promotion.
作者
冯丽丽
郭涛
刘超
FENG Lili;GUO Tao;LIU Chao(Ningxia Hui Autonomous Region Traditional Chinese Medicine Research Institute,Ningxia Hui Autonomous Region,Yinehuan 750021,China)
出处
《中国民族民间医药》
2018年第14期81-84,共4页
Chinese Journal of Ethnomedicine and Ethnopharmacy
基金
自治区卫生计生委重点研究项目(2016-NW-052)
关键词
颈动脉粥样硬化斑块
脉管通胶囊
辛伐他汀
中西医结合
Carotid Atherosclerotic Plaques
Mai Guan Tong Capsule
Simvastatin
Integrative Medicine
