摘要
目的探讨胰腺腺泡细胞癌(PACC)的临床及超声声像图特征。方法收集1999年1月至2015年12月在北京协和医院就诊,经病理证实为PACC的患者13例,其中,男性9例,女性4例,年龄30~76岁,平均年龄(53.9±12.4)岁。临床症状包括腹痛、恶心、胸闷、消瘦。对13例PACC患者的临床、超声及超声造影表现进行分析。结果 13例患者中,5例(38.5%)患者血清肿瘤标志物浓度升高。肿瘤发生于胰腺体尾部8例(61.5%),胰头部4例(30.8%),1例累及全胰(7.7%)。肿瘤最大径2.0~14.4 cm,囊实性结构4例(30.8%),边界清晰者6例(60.0%),呈外凸性生长5例(38.5%),胰胆管扩张3例(23.1%)。肝转移4例(30.8%),淋巴结转移3例(23.1%),累及血管4例(30.8%)。2例行超声造影,1例动脉期等增强,1例高增强。结论 PACC超声表现多为边界清、外凸、体积较大、血供相对丰富的囊实性肿物,有一定特征性。
Objective To explore the clinical and sonographic characteristics of pancreatic acinar cell carcinoma（PACC）. Methods The clinical data and abdominal sonographic findings of 13 cases of PACC identified with pathology were reviewed, including contrast-enhanced ultrasound（CEUS） images. There were 9 males and 4 females with the average of 53.9 years old. Symptoms included upper abdominal pain, nausea, chest distress and weight loss. Results The serum level of tumor maker was elevated in only 5 cases. Eight masses（61.5%） were located in the pancreatic body-tail, 4（30.8%） in the head, the whole pancreas was involved in 1 case. The mean maximal diameter was 8.0 cm. Four lesions（30.8%） presented as solid-cystic mass. Well-defined border was showed in 6 cases（60.0%）. Exophytic type was observed in 5 cases（38.5%）. Pancreatic ductal dilation was seen in 3 cases（23.1%）, in which 2 cases showed obstruction of common biliary duct. Liver metastasis was assessed in 4 patients（30.8%）, and lymph node metastasis in 3 cases（23.1%）. Vessels were invaded in 4 cases（30.8%）. In 2 cases by CEUS, one showed arterial iso-enhancement, the other with strong enhancement. Conclusion Certain characteristic clinical and ultrasonographic features could be revealed in PACC, as a sizable, exophytic, solid-cystic and relatively hypervascular mass with well-definded border.
作者
谭莉
吕珂
仲光熙
张璟
张青
孝梦甦
桂阳
周桂丽
姜玉新
Tan Li;Lyu Ke;Zhong Guangxi;Zhang Jing;Zhang Qing;Xiao Mengsu;Gui Yang;Zhou Guili;Jiang Yuxin(Department of Ultrasound,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;Department of Ultrasound,Shenzhen Sun Yat-sen Cardiovascular Hospital,Shenzhen 518112,China)
出处
《中华医学超声杂志（电子版）》
CSCD
2017年第6期428-432,共5页
Chinese Journal of Medical Ultrasound(Electronic Edition)
基金
国家卫生和计划生育委员会公益性行业科研专项项目(201402001)
中国医学科学院医学与健康科技创新工程经费资助(消化道肿瘤)(2016-I2M-3-005)
关键词
超声检查
胰腺肿瘤
癌
腺泡细胞
Ultrasonography
Pancreatic neoplasms
Carcinoma
acinar cell
