摘要
目的探讨临床翼状胬肉切除联合丝裂霉素C术后巩膜融解的疗效与预防。方法选取本院2015年7月~2017年5月接收的行临床翼状胬肉切除联合丝裂霉素C术的54例患者(共54眼)为观察组,术后均未继续使用激素类眼液,54例患者选用滴眼液均为非激素类,同时选用贝复舒眼膏,使用滴眼液,直到完全修复。另选择2013年7月~2015年6月收治的36例患者为对照组,单纯行翼状胬肉切除术,比较两组患者临床治疗效果。结果术后所有患者均以药物进行保守治疗,治疗后患者巩膜外观平整,得以完全恢复。观察组患者临床治疗有效率为96.30%,对照组患者临床治疗有效率为80.56%,所有患者巩膜外观平整,得以完全修复,无一例出现术后并发症;观察组无一例患者出现复发情况,对照组有2例患者出现复发,翼状胬肉切除联合丝裂霉素C术与单纯行翼状胬肉切除术相比较安全性较低,但是临床治疗效果较佳,所以在应用时在用量上需多加注意,保证患者安全。结论翼状胬肉切除联合丝裂霉素C在临床中能够有效提高临床疗效,但是手术中会导致患者局部组织被烧伤,所以在临床治疗时注意丝裂霉素C的使用浓度及操作时间,以防止巩膜融解的发生。
Objective To investigate the curative effect of pterygium excision combined with mitomycin C on scleral melting and the prevention of pterygium excision. Methods 54 patients（54 eyes）with clinical pterygium excision combined with mitomycin C who were admitted in our hospital from July 2015 to May 2017 were selected as the observation group, and they were not treated with hormones eye drops after surgery continuously. The 54 patients were given non-hormones eye drops, as well as Beifushu eye ointment until complete recovery. 36 patients admitted in our hospital from July 2013 to June 2015 were chosen as the control group and were treated with pterygium excision. The clinical treatment effect between the two groups was compared. Results All patients underwent conservative treatment with drugs after surgery. After treatment, the scleral appearance of the patients was flat and recovered completely. The effective rate of clinical treatment was 96.30% in 54 patients of the observation group and 80.56% in 36 patients of the control group. The scleral appearance of all patients was flat and completely repaired without any complications. No patient had recurrence in the observation group. And 2 patients had recurrence in the control group. Pterygium excision combined with mitomycin C surgery had less safety and better clinical treatment effect compared with simple pterygium excision, which would be paid more attention to in the application to ensure the safety of patients. Conclusion Pterygium excision combined with mitomycin C can effectively improve the clinical efficacy in clinical practice, but will lead to local tissue burns during the operation. Therefore, the concentration and operating time of mitomycin C in the clinical treatment should be paid attention to, to prevent the occurrence of scleral melting.
作者
姜英梅
杨雪琦
王秀英
JIANG Yingmei;YANG Xueqi;WANG Xiuying(Department of Ophthalmology,Second Affiliated Hospital of Mudanjiang Medical College,Mudanjiang 157000,China)
出处
《中国现代医生》
2018年第13期68-70,共3页
China Modern Doctor
