摘要
老年肺部感染是特指年龄≥65岁的老年人所患主要由细菌、病毒、支原体等各种病原体侵袭引起的终末气道、肺泡及肺间质的感染性疾病。由于老年人免疫力下降、机体功能退化、慢性基础疾病多,肺部感染患病率及致死率明显升高。而老年肺部感染患者血清ChE与NT-proBNP水平有显著变化,且与疾病严重程度和死亡风险也显著相关。检测血清ChE与NT-proBNP水平,方法简便、安全,临床上易广泛开展。因此深入了解胆碱酯酶、氨基末端脑钠肽前体在老年肺部感染患者中的临床应用进展,对老年肺部感染诊断、预后评估、病情监测有重大意义。
Pneumonia is a respiratory disease characterized by inflammation of the lung parenchyma（excluding the bronchi） with congestion caused by viruses or bacteria or irritants. Pneumonia in the elderly refers to special pneumonia that the people suffer from who older than sixty-five years old in this article. The morbidity rate and fataity rate of pneumonia in the elderly are obviously higher than other age groups because of reduced immunity,deterioration of body function and many chronic underlying diseases. The level of cholinesterase and NT-proBNP conspicuously change in the elderly Pneumonia patients,and both are also related to the severity of the disease and the risk of death. As simple and safe inspection method,cholinesterase and NT-proBNP can be widely used in clinical work,recognizing cholinesterase and NT-proBNP research progress in the application of diagnosis the value of prognosis evaluation of the elderly patients with pneumonia,recurrence monitoring has great significance.
作者
张婷
袁开芬
赵国厚
蒋成
ZHANG Ting;YUAN Kaifen;ZHAO Guohou;JIANG Cheng(The 3th department of respiratory in Kunming medical university second affiliated hospital,Yunnan 650101;Yunnan Xingxing Occupations institute,Kunming 650501,China)
出处
《中国老年保健医学》
2018年第4期86-88,共3页
Chinese Journal of Geriatric Care
关键词
老年肺部感染
胆碱酯酶
NT-PROBNP
预后评估
Pneumonia in the elderly people
Cholinesterase
NT-proBNP
diagnosis
Prognosis evaluation
