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Serum Antioxidant Enzymes SOD and CAT of Nile Tilapia(Oreochromis niloticus)in Response to Pesticide Methomyl and Recovery Pattern

Serum Antioxidant Enzymes SOD and CAT of Nile Tilapia(Oreochromis niloticus) in Response to Pesticide Methomyl and Recovery Pattern
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摘要 Tilapia were exposed to sub-lethal concentrations of 0, 0.2, 2, 20 or 200 μg/L for 30 d, and then transferred to methomyl-free water for 18 d. CAT and SOD in tilapia serum were examined at 0, 6, 12, 18, 24 and 30 d after methomyl exposure and at 18 d after transferring to methomyl-free water. There were no significant changes in antioxidants activities in tilapia exposed to 0.2 μg/L. Significant increases in SOD, CAT were observed following methomyl exposure to 2, 20 or 200 μg/L, suggesting the presence of oxidative stress. Thus, the 0.2 μg/L methomyl might be considered the no observed adverse effect level. Recovery data showed that the effects produced by lower concentration of 20 μg/L were reversible but not at the higher concentration of 200 μg/L. Tilapia were exposed to sub-lethal concentrations of 0, 0.2, 2, 20 or 200 μg/L for 30 d, and then transferred to methomyl-free water for 18 d. CAT and SOD in tilapia serum were examined at 0, 6, 12, 18, 24 and 30 d after methomyl exposure and at 18 d after transferring to methomyl-free water. There were no significant changes in antioxidants activities in tilapia exposed to 0.2 μg/L. Significant increases in SOD, CAT were observed following methomyl exposure to 2, 20 or 200 μg/L, suggesting the presence of oxidative stress. Thus, the 0.2 μg/L methomyl might be considered the no observed adverse effect level. Recovery data showed that the effects produced by lower concentration of 20 μg/L were reversible but not at the higher concentration of 200 μg/L.
出处 《Agricultural Biotechnology》 CAS 2018年第5期264-267,273,共5页 农业生物技术(英文版)
基金 Supported by the Special Scientific Research Funds for Central Non-profit Institutes,Chinese Academy of Fishery Sciences(No.2015C02XK01) the Natural Science Foundation of Jiangsu Province for Youth(No.BK20150117) the China Agriculture Research System(CARS-46)
关键词 METHOMYL SERUM TILAPIA ANTIOXIDANTS RECOVERY Methomyl Serum Tilapia Antioxidants Recovery
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