摘要
目的 了解杭州市城市化社区人群血脂异常率及血脂水平的变化趋势.方法 采用随机整群抽样方法,抽取2011—2016年连续6年接受健康体检的年龄≥24岁城市化社区户籍居民1485名（男性677名,女性808名）,所有对象空腹测定血三酰甘油（TG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）水平,采用χ2检验分析6年间该人群血脂异常率的趋势、重复测量方差分析血脂水平的变化.结果 ①2011—2016年,1485名居民的总血脂异常率分别为33.2%（493/1485）、30.5%（453/1485）、30.4%（452/1485）、26.5%（394/1485）、26.3%（391/1485）、25.1%（373/1485）,呈逐年下降趋势（χ2=36.051,P〈0.01）,其中高TG血症率在6年间比较差异无统计学意义（χ2=10.081,P〉0.05）.②TG、TC、LDL-C、HDL-C水平在6年间比较差异均有统计学意义（F分别为4.876、33.033、170.254、58.442,P均〈0.01）,其中LDL-C水平在2011年最高,为（3.02±0.29）mmol/L,在2016年最低,为（2.72±0.71）mmol/L,HDL-C水平则在2011年最低,为（1.35±0.30）mmol/L,在2016年最高（1.44±0.33）mmol/L.③时间-性别组交互效应分析：TC和HDL-C水平在男女分组中随时间而有不同的变化趋势（F分别为2.556、4.982,均P〈0.05）,其中男性组TC水平自2012年后较女性组下降趋势明显.④时间-年龄组交互效应：TC、LDL-C水平在年龄分组随时间而有不同的变化趋势,老年组的TC和LDL-C水平下降趋势较青年组和中年组更为显著（F分别为10.328、3.085,P均〈0.01）.结论 本社区人群血脂总体呈改善趋势,而高TG血症无明显改善趋势,应继续对该社区进行血脂监测,特别是要加强高TG血症的防控.
Objective To understand the dyslipidemia rate and trend of blood lipid level in an urban community in Hangzhou. Methods A total of 1 485 urban community residents aged 24 years or older who had participated in health checkup over 6 years, from 2011-2016, were selected by random cluster sampling. Fasting blood Triglyceride （TG）, total cholesterol （TC）, low density lipoprotein cholesterol （LDL-C）, and high density lipoprotein cholesterol （HDL-C） levels were measured in all subjects. A X2 test was used to analyze the dyslipidemia rate trend, and an ANOVA of repeated measurement was conducted to observe the blood lipid level changes. Results From 2011 to 2016, the total abnormal rates of blood lipids in 1 485 residents were 33.2% （493/1 485）, 30.5% （453/1 485）, 30.4% （452/1 485）, 26.5% （394/1 485）, 26.3% （391/1 485）, and 25.1% （373/1 485）, respectively, which showed a declining trend year-by-year （χ2= 36.051, P〈0.01）. Among these results, however, the high TG rate did not significantly differ from year-to-year （χ2=10.081, P〉0.05）. The TG, TC, LDL-C, and HDL-C levels statistically differed over the 6 years （F=4.876, 33.033, 170.254, 58.442, respectively, all P〈0.01）. LDL-C was the highest in 2011 [（3.02±0.29） mmol/L] and the lowest in 2016 [（2.72±0.71） mmol/L], while HDL-C was the highest in 2016 （1.44±0.33 mmol/L） and the lowest in 2011 [（1.35±0.30） mmol/L]. Time-sex group interaction effect analysis： TC and HDL-C levels showed different trends over time between men and women （F=2.556, 4.982, respectively, all P〈0.05）, and the TC level in the male group was significantly lower than in the female group, since 2012. Interaction effect of time age group： TC and LDL-C levels showed different trends between age groups over time, and the declining trend of TC and LDL-C in the elderly group was more significant than in the young or middle age group （F=10.328, 3.085, respectively, all P〈0.01）. Conclusions The community population showed an overall improvement in blood lipid levels; however, there was no significant improvement in high TG levels. It is necessary to continue monitoring blood lipid levels in the community, especially to strengthen the prevention and control of high TG levels.
作者
马程乘
叶小琴
葛阳
戴文芸
胡芳
谢文倩
Ma Chengcheng;Ye Xiaoqin;Ge Yang;Dai Wenyun;Hu Fang;Xie Wenqian(Dinglan Street Community Health Service Center,Hangzhou 310021,China;Xiaoshan District Center for Disease Control and Prevention,Hangzhou 310006,China;Sijiqing Street Community Health Service Center,Hangzhou 310016,China)
出处
《中华健康管理学杂志》
CAS
2018年第4期307-312,共6页
Chinese Journal of Health Management
基金
中国成人血脂异常健康管理服务试点项目（2013IHECC-DLM）
关键词
血脂异常
社区参与研究
人群监测
Dyslipidemia
Community-based participatory research
Population surveillance
