摘要
目的:观察清胃降逆法治疗非糜烂性反流病的临床疗效。方法:将200例非糜烂性反流病患者按随机数字表法分为试验组和对照组,每组100例。两组患者疗程均为4周。观察两组患者的临床疗效和症状疗效。治疗结束后对治疗显效患者随访6个月,观察两组患者的复发情况。结果:经4周治疗后,试验组有效率为90.0%,对照组有效率为64.0%,试验组优于对照组,差异有统计学意义(P<0.05);两组患者胸骨后灼痛、烧心、嗳气等症状比较,试验组优于对照组,差异均有统计学意义(P<0.05);治疗后6个月随访,复发情况比较,试验组优于对照组,差异有统计学意义(P<0.05)。结论:清胃降逆法治疗非糜烂性反流病疗效显著,且复发率低。
Objective：To observe the clinical efficacy of Qingwei Jiangni Method in treatment of non-erosive reflux disease. Meth- ods ：200 patients with non-erosive reflux disease were divided into experimental group and control group according to random num- ber table, with 100 cases in each group. The experimental group was treated with Guanyanling Granules （made by Yancheng Hos- pital of Traditional Chinese Medicine）, 10g each time, 3 times a day. The control group was treated with Omeprazole capsule （made by Jiangsu Lianhuan Pharmaceutical Co. , Ltd. ） ,20 mg each time, twice a day. Both groups of patients were treated for 4 weeks. The clinical efficacy of the 2 groups was observed. After the treatment, the patients with markedly effective treatment were followed up for 6 months and the recurrence condition of the two groups was observed. Results ： After 4 weeks of treatment, the ef- fective rate of the experimental group was 90.0%, and the effective rate of the control group was 64.0%. The experimental group was superior to that of the control group, the difference was statistically significant （P 〈 0.05 ）. The improvement in symptoms of burning pain after the sternum, heartburn and hernia in the experimental group was better than that of the control group （ P 〈 0. 05）. The RDQ scores of the two groups were significantly better than those of the control group （P 〈0.01 ）. At 6 months after treatment, the recurrence condition was compared and that of the experimental group was superior to that of the control group （P 〈 0.05 ）. Conclusion ： Oingwei Jiangni method is effective in treating for non-erosive reflux disease with low recurrence rate.
作者
黄河
黄福斌
张阳
刘柱成
仇玕
HUANG He;HUANG Fubin;ZHANG Yang;LIU Zhucheng;QIU Gan(Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine,Yancheng Jiangsu China 22400)
出处
《中医学报》
CAS
2018年第9期1774-1776,共3页
Acta Chinese Medicine
基金
江苏省中医药局科技项目{苏中科教【2015】9号YB2015130}
关键词
非糜烂性反流病
清胃降逆法
管炎灵颗粒
non-erosive reflux disease
Qingwei Jiangyin method
Guanyanling Granule
