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疏血通注射液联合小牛血清去蛋白注射液对急性缺血性脑梗死患者凝血功能及预后的影响 被引量:1

Effect of Shuxuetong injection combined with deproteinised calf blood injection on coagulation function and prognosis in patients with acute ischemic cerebral infarction
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摘要 目的探讨对急性缺血性脑梗死患者给予疏血通注射液联合小牛血清去蛋白注射液治疗后的凝血功能变化,并观察预后效果。方法回顾性分析2016年1月至2017年10月收治的85例急性缺血性脑梗死患者的资料,其中有45例给予疏血通注射液联合小牛血清去蛋白注射液治疗,为A组,剩余40例实施小牛血清去蛋白注射液治疗,为B组。对比两组患者的凝血功能、神经功能缺损评分(NIHSS评分)及不良预后发生情况。结果治疗后,两组血浆PT和APTT均延长,血浆D-D、FIB水平、NIHSS评分均降低,且A组上述指标均优于B组(P<0.05)。A组不良预后总发生率低于B组(P<0.05)。结论疏血通注射液联合小牛血清去蛋白注射液治疗急性缺血性脑梗死,能够改善患者的凝血功能,减轻其神经功能缺损,减少不良预后。 Objective To explore the changes of coagulation function after treatment by Shuxuetong injection combined with deproteinised calf blood injection in patients with acute ischemic cerebral infarction, and to observe the prognosis effect. Methods The data of 85 patients with acute ischemic cerebral infarction from January 2016 to October 2017 were retrospectively analyzed. Among them, 45 cases who were treated with Shuxuetong injection combined with deproteinised calf blood injection were selected as group A. Another 40 cases who were treated with deproteinised calf blood injection were selected as group B. The coagulation function, the neurological deficit scores(NIHSS scores) and incidence of adverse prognosis in the two groups were compared. Results After treatment, the PT and APTT prolonged, and the levels of D-D,FIB and NIHSS scores decreased in the two groups, and those in the group A were better than the group B(P〈 0.05). The total incidence of adverse prognosis in the group A was lower than that in the group B(P〈 0.05). Conclusion The Shuxuetong injection combined with deproteinised calf blood injection in the treatment of acute ischemic cerebral infarction can improve coagulation function of patients, reduce neurological impairment and adverse prognosis events.
作者 李张霞 杨飞虎 LI Zhang-xia;YANG Fei-hu(No.15 Ward of Neurology Department,Xianyang Hospital of Yan'an University,Xianyang 712000,China)
出处 《临床医学研究与实践》 2018年第30期9-10,共2页 Clinical Research and Practice
关键词 疏血通注射液 小牛血清去蛋白注射液 急性缺血性脑梗死 Shuxuetong injection deproteinised calf blood injection acute ischemic cerebral infarction
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