摘要
目的了解温州市出生缺陷的发展趋势及终止妊娠特征,为进一步制定出生缺陷干预措施提供依据。方法对2007-2015年来温州市产前诊断中心终止妊娠病例2505例围产儿出生缺陷监测并进行分析,根据《中国出生缺陷分类编码系统》进行缺陷系统分类,以SPSS软件进行描述分析。结果 2007~2015年主要缺陷系统是中枢神经、心血管、肌肉骨骼系统,各占24.9%、22.6%、22.2%。染色体异常共316例,其中21-三体155例,占49.1%;18-三体55例,占17.4%。所有类型的缺陷系统构成均呈非线性趋势增长。结论中枢神经系统、心血管系统、肌肉骨系统可作为重点开展产前检查的对象,染色体异常仍是我国产前检查并终止妊娠的主要问题,要强加重视,做好防范工作。
Objective：To understand the development trend of Wenzhou City,termination of pregnancy and birth defects characteristics,provide the basis for further development of birth defects interventions. Methods：2007 to 2015 in Wenzhou City,prenatal diagnosis center do review the termination of pregnancy cases,2505 cases of birth defects monitoring and analysis to Excel establish a database;according to ＂China birth defects classification and coding system＂ defect taxonomy;with SPSS descriptive analysis software. Results：2007 to 2015,the main defect of the central nervous system,cardiovascular,musculoskeletal system,respectively,24.9%,22.6%,22.2%. A total of 316 cases of chromosomal defects,including trisomy 21 155 cases,accounting for 49.1%;followed by trisomy 18 and 55 cases,accounting for 17.4%. All types of defects showed a nonlinear system constitutes a growing trend. Conclusion：Central nervous system,cardiovascular,musculoskeletal system can focus on objects as prenatal care,chromosomal abnormalities is still the main issue of prenatal testing and termination of pregnancy,to impose pay attention and do preventive work.
作者
徐雪琴
林小玲
郑允樵
王瑞璞
唐少华
XU Xue-qin;LIN Xiao-ling;ZHENG Yun-qiao;WANG Rui-pu;TANG Shao-hua(Department of Clinical Laboratory,Wenzhou Central Hospital,Wenzhou,Zhejiang 325000,China)
出处
《中国优生与遗传杂志》
2018年第9期74-75,59,共3页
Chinese Journal of Birth Health & Heredity
基金
浙江省卫计委项目(2015RCB027)
温州市公益性科技计划项目(Y20140745)
关键词
产前检查
终止妊娠
出生缺陷
Prenatal dignosis
Termination of pregnancy prenatal~ Birth defects
