摘要
目的探讨2型糖尿病患者合并胃轻瘫的危险因素。方法前瞻性纳入2018年6月门诊2型糖尿病患者245例进行横断面研究,通过自制调查问卷收集患者人口学特征信息(年龄、性别、体质量指数)、糖尿病情况(病程、用药方式、合并症)、实验室指标(空腹血糖和糖化血红蛋白水平),通过胃轻瘫主要症状指数(Gastroparesis Cardinal Symptoms Index, GCSI)量表调查患者是否存在胃轻瘫情况及其严重程度。结果该组2型糖尿病患者胃轻瘫的发生率为13.9%(34/245),胃轻瘫的最常见的临床症状依次为腹胀、胃部饱胀感和早饱,以上症状的发生率分别为67.6%(23/34)、62.9%(18/34)和44.1%(15/34)。胃轻瘫患者与无胃轻瘫患者在年龄、性别、体质量指数、糖尿病用药方式、合并症方面差异无统计学意义(P>0.05),胃轻瘫患者糖尿病病程较长、空腹血糖水平较高、糖化血红蛋白水平较高(P<0.05)。结论 2型糖尿病患者胃轻瘫发生率较高,临床症状明显,严重影响患者生活质量和身心健康。2型糖尿病患者胃轻瘫的发生与糖尿病控制不佳、空腹血糖偏高、糖尿病病程较长有关。
Objective To investigate the risk factors of patients with type 2 diabetes complicated with gastroparesis. Methods A prospective study of 245 patients with type 2 diabetes mellitus in June 2018 was conducted in a cross-sectional study. The demographic characteristics （age, gender, body mass index） and diabetes status （disease, medication, comorbidities） were collected through a self-made questionnaire）, laboratory indicators （fasting blood glucose and glycated hemoglobin levels）, through the Gastroparesis Cardinal Symptoms Index （GCSI） scale to investigate whether the patient has gastroparesis and its severity. Results The incidence of gastroparesis in patients with type 2 diabetes was 13.9% （34/245）. The most common clinical symptoms of gastroparesis were abdominal distension, stomach fullness and early satiety. The incidence of these symptoms was respectively of 67.6% （23/34）, 62.9% （18/34） and 44.1% （15/34）. There were no significant differences in age, gender, body mass index, diabetes medication, and comorbidities between patients with gastroparesis and those without gastroparesis （P〉0.05）. Patients with gastroparesis had longer duration of diabetes and higher fasting blood glucose levels and glycated hemoglobin levels were higher （P〈0.05）. Conclusion The incidence of gastroparesis is higher in patients with type 2 diabetes, and the clinical symptoms are obvious, which seriously affects the quality of life and physical and mental health of patients. The occurrence of gastroparesis in patients with type 2 diabetes is associated with poor control of diabetes, high fasting blood glucose, and long duration of diabetes.
作者
林燕
张发钦
李海涛
LIN Yan;ZHANG Fa-qin;LI Hai-tao(Department of Gastroenterology,Fuzhou Second Hospital Affiliated to Xiamen University,Fuzhou,Fujian Province,350007 China;Department of Gastroenterology,Fuzhou General Hospital of PLA,Fuzhou,Fujian Province,350025 China)
出处
《糖尿病新世界》
2018年第18期42-44,共3页
Diabetes New World Magazine
基金
福建省自然科学基金项目(2017J01321)
关键词
胃轻瘫
2型糖尿病
空腹血糖
Gastroparesis
Type 2 diabetes
Fasting blood glucose
