摘要
目的探究重症急性肾功能衰竭患者分别利用连续性肾脏替代疗法、间歇性血液透析疗法进行治疗所获得的临床效果差异。方法本次研究以2016年4月至2017年3月为研究时间段,选择在此期间入我院就诊患者92例作为研究对象,均明确重症急性肾功能衰竭诊断,按照就诊先后顺序将患者分成对照组及观察组,每组各46例;对照组行间歇性血液透析疗法,观察组则行连续性肾脏替代疗法,分析两组患者治疗效果比较。结果观察组治疗后BUN、Scr水平、PLT计数均显著低于对照组及治疗前(P<0.05),但APTT水平显著高于对照组及治疗前(P<0.05);观察组1年生存率87.76%(43/49)显著高于对照组的61.90%(26/42)(P<0.05);观察组治疗后APCHE II评分均显著低于对照组及治疗前(P<0.05);观察组治疗后LBP、ARY发生次数均显著低于对照组(P<0.05)。结论重症急性肾功能衰竭患者利用连续性肾脏替代疗法进行治疗的临床效果优于间歇性血液透析疗法,其生存率获得显著提高,而生存时间也得以延长。
Objective to analyze clinical effect of continuous renal replacement therapy and intermittent hemodialysis in treatment of severe acute renal failure. Methods choose 91 severe acute renal failure patients in our hospital from April 2016 to March 2017, divide them into observation and control group according to random principles, 49 cases in observation group were treated with continuous renal replacement therapy, and 42 cases in control group with intermittent hemodialysis. Compare treatment effect of two groups. Results after treatment, BUN, Scr and PLT levels in observation group were significantly lower than control group and before treatment（P〈0.05）, and APTT level of observation group was significantly higher than control group before treatment（P〈0.05）, and 1 year survival rate of observation group was 87.76%（43/49）, significantly higher than 61.90%（26/42）of control group（P〈0.05）, APCHE II scores of observation group after treatment were significantly lower than control group and that of before treatment（P〈0.05）. LBP and ARY frequency of observation group was significantly lower than control group（P〈0.05）. Conclusion clinical effect of continuous renal replacement therapy is better than intermittent hemodialysis for severe acute renal failure, which can improve survival rate and prolong survival time of significantly.
作者
范孟静
FAN Meng-jing(Fengtai Youanmen Hospital of Beijing,Beijing,100069)
出处
《智慧健康》
2018年第12期112-114,共3页
Smart Healthcare
