摘要
目的观察重症胆源性胰腺炎逆行胰胆管造影(ERCP)术后早期经空肠营养管注入生大黄液对患者血清淀粉酶(AMY)、C-反应蛋白(CRP)及胃肠功能的影响。方法将118例重症胆源性胰腺炎患者随机分为治疗组(60例)和对照组(58例),2组均行ERCP术以解除胆道梗阻,术后均予全身综合治疗,治疗组在全身综合治疗的基础上早期经空肠营养管注入生大黄液。比较2组患者的血清AMY、胃肠功能恢复时间及CRP含量。结果治疗组血清AMY恢复时间及胃肠功能恢复时间均明显短于对照组,2组比较差异均有统计学意义(P<0.05或P<0.01);治疗组术后48 h CRP含量明显降低,与同组术前比较差异有统计学意义(P<0.05),且治疗组降低程度明显高于对照组,2组术后48 h比较差异有统计学意义(P<0.05)。结论早期经肠内营养管注入生大黄液能明显降低重症胆源性胰腺炎患者ERCP术后的CRP含量,缩短血清AMY及胃肠功能恢复时间,从而缩短病程,且价格低廉,值得临床推广应用。
Objective To observe the effects of raw Dahuang Ye on AMY, CRP and injected through the jejunal feeding tube in the early postoperative period of severe gallston gastrointestinal function e pancreatitis after ER- CP.Metbods A total of 118 cases with severe gallstone pancreatitis were randomly divided into treatment group （60 cases） and control group （58 cases）. Both groups were performed ERCP to resolve bile duct obstruction with postoperative systemic comprehensive treatment,and the treatment group was added with raw Dahuang Ye injected through the jejunal feeding levels of the 2 groups were tube.The serum level of AMY recovery time, gastrointestinal function recovery time, CRP compared .Results Recovery time of the serum amylase level and gastrointestinal function of the treatment group was significantly shorter than that of the control group, there was statistical difference （P〈0.05 or P〈0.01 ） ;and CRP level at 48 h after operation in the treatment group decreased significantly, there was statistical difference compared with the same group before operation, moreover, the level of the treatment group decreased significantly higher than that of the control group, and the differehce was statistically significant at 48 h after operation between the 2 groups （ P 〈 0.05 ）. Conclusion The therapy significantly reduces CRP level, and shortens recovery time of gastrointestinal function and serum AMY.Thus, it shortens the course of disease with low price and deserves the clinical expansion and application.
作者
王苏丽
姚茹
周毅
张岁利
陈荣利
WANG Suli;YAO Ru;ZHOU Yi;ZHANG Suili;CHEN Rongli(Department of Digestion,No.451 Hospital of the PLA,Xi＇an,Shaanxi,710054,China)
出处
《甘肃中医药大学学报》
2018年第5期77-80,共4页
Journal of Gansu University of Chinese Medicine
关键词
重症胆源性胰腺炎
逆行胰胆管造影术
生大黄液
C-反应蛋白
血清淀粉酶
胃肠功能
临床观察
Severe gallstone pancreatitis
endoscopic retrograde cholangiopancreatography （ ERCP ）
rawDahuang Ye
C-reactive protein （ CRP ）
serum amylase （AMY）
gastrointestinal function
clinical observation
