摘要
目的观察腕踝针对颈椎病患者的镇痛疗效及血浆?-内啡肽(?-EP)、P物质(SP)含量的影响。方法将60例颈椎病急性发作颈痛患者随机分为腕踝针组和传统针刺组,观察两组不同时点的镇痛疗效和治疗前后?-EP、SP含量的变化。结果两组治疗后症状、体征积分较治疗前明显上升,但治疗24 h后,腕踝针组优于传统针刺组(P<0.01),治疗30 min、1个疗程后,两组间比较差异无统计学意义(P>0.05)。两组VAS评分均较治疗前明显降低,但在治疗30 min、24 h后,腕踝针组优于传统针刺组(P<0.05,P<0.01),治疗1个疗程后,两组无统计学差异(P>0.05)。两组镇痛疗效在治疗30 min、24 h后比较差异有统计学意义(P<0.05),治疗1个疗程后无统计学差异(P>0.05)。两组治疗后血浆?-EP含量均升高(P<0.001,P<0.05),腕踝针组优于传统针刺组(P<0.01);两组血浆SP含量均降低(P<0.001,P<0.05),腕踝针组优于传统针刺组(P<0.05)。结论腕踝针治疗颈椎病颈痛疗效肯定,且腕踝针疗法即刻镇痛作用优于传统针刺法,其作用机制可能与引起体内血浆?-EP的释放与SP的抑制有关。
Objective To investigate the analgesic effect of wrist-ankle acupuncture and its impact on plasma β-endorphin and substance P contents in patients with cervical spondylosis-induced neck pain. Method Sixty patients with neck pain caused by acute attack of cervical spondylosis were randomized to wrist-ankle acupuncture and conventional acupuncture groups. The analgesic effects at different time points and post-treatment changes in β-EP and SP contents were observed in the two groups. Result The symptom and sign scores increased significantly in the two groups after treatment compared with before, increased more in the wrist-ankle acupuncture group than in the conventional acupuncture group after 24 hrs of treatment （P〈0.01） and had no statistically significant differences between the two groups after 30 min of and one course of treatment （P〉0.05）. The VAS score decreased significantly in the two groups after treatment compared with before, decreased more in the wrist-ankle acupuncture group than in the conventional acupuncture group after 30 min and 24 hrs of treatment （P〈0.05, P〈0.01） and had no statisticallysignificant difference between the two groups after one course of treatment （P〉0.05）. There was a statistically significant difference in the analgesic effect between the two groups after 30 min and 24 hrs of treatment （P〈0.05） but no after one course of treatment （P〉0.05）. Plasma β-EP content increased in both groups after treatment and increased more in the wrist-ankle acupuncture group than in the conventional acupuncture group （P〈0.001）. Plasma SP content decreased in both groups after treatment and decreased more in the wrist-ankle acupuncture group than in the conventional acupuncture group （P〈0.05）. Conclusion Wrist-ankle acupuncture has a definite therapeutic effect on cervical spondylosis-induced neck pain. The immediate analgesic effect of wrist-ankle acupuncture is better than that of conventional acupuncture. Its mechanism of action may be related to promoting plasma β-EP release and inhibiting SP release.
作者
陈盼碧
王甜
杨孝芳
崔瑾
夏志鸿
CHEN Pan-bi;WANG Tian;YANG Xiao-fang;CUI Jin;XIA Zhi-hong(Guiyang College of Traditional Chinese Medicine,Guiyang 550002,China;Foshan Nanhai Distric third People＇s Hospital,Guangzhou 528244,China;Guiyang College of Traditional Chinese Medicine Second Hospital,Guiyang 550003,China)
出处
《上海针灸杂志》
2018年第12期1419-1423,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
贵州省中医药管理局课题(QZYY2010-33)
关键词
针刺疗法
颈椎病
颈痛
腕踝针
血浆Β-内啡肽
血浆P物质
Acupuncture therapy
Cervical spondylosis
Neck pain
Wrist-ankle acupuncture
Plasma β-endorphin
Plasma substance P
