摘要
目的 探讨帕金森病Vim核立体定向射频毁损灶的MRI表现及其与疗效的关系。方法 2 3例帕金森病患者接受Vim核立体定向射频毁损术 ,在手术后的早期 (16例 )、晚期 (7例 )进行MRI随访 ,了解毁损灶的MRI表现、大小及其与疗效的关系 ,并且计算毁损灶的位置与原靶点坐标的误差。结果 16例患者在术后 3～ 7天复查MRI ,T1加权像 :中心为细小的长T1低信号点 ,中间为短T1高信号环 ,最外为长T1低信号环 ,周边有不规则的水肿带 ;T2 加权像 :中心为细小的长T2 高信号点 ,中间为短T2 低信号环 ,最外为长T2 高信号环 ,周边有不规则的水肿带。 7例患者术后 1～ 2年复查MRI,毁损灶的MRI表现为长T1长T2 类圆形信号。毁损灶的位置与原靶点的误差小于 1mm。结论 帕金森病立体定向射频毁损灶的大小与毁损的温度、时间、毁损针的直径和长度成正比 ,晚期MRI随访提示如果靶点位置正确 ,毁损灶大小在 5 .0mm× 5 .2mm× 8.1mm左右 。
Objective To analysis the relationship between the appearance of radiofrequency lesions on MRI and the curative effect of parkinson's disease. Methods 23 cases who underwent stereotactic Vim-thalamotomy had magnetic resonance imaging, 16 cases were in 3～7 days and 7 cases were in 1～2 years after operations. We calculated the volume of lesions, analysed the relationship between the appearance on MRI and the curative effect, and measured the error. Results The appearance of 16 cases in 3～7 days after operations was consisted of three part on MRI: the inner was hypointense in T 1-weight and hyperintense in T 2-weight, the middle was hyperintense in T 1-weight and hypointense in T 2-weight and the outer was hypointense in T 1-weight and hyperintense in T 2-weight. The appearance of 7 cases in 1～2 years after operations on MRI was hypointense in T 1-weight and hyperintense in T 2-weight. The error was less than 1 mm. Conclusion The lesions'volume was related to the lesioning temperature, duration, the electrode tip diameter and the exposed tip length. If the volume was about 5 mm×5.2 mm×8.1 mm,the effect was good. [
出处
《立体定向和功能性神经外科杂志》
2002年第3期141-143,共3页
Chinese Journal of Stereotactic and Functional Neurosurgery
