摘要
目的 :获取本地区正常人群鼻咽部脑膜炎奈瑟菌携带情况 ,为政府制定预防和控制流行性脑脊髓膜炎暴发流行提供科学决策依据。方法 :随机抽检正常人群 (按人群防疫监测共分四组 :2～ 4岁、6～ 8岁、9～ 12岁、2 5～ 39岁组 )鼻咽拭子进行培养、分离、鉴定及血清分型 ,按《全国临床检验操作规程》进行。结果 :4 0 3人共检出 2 2株脑膜炎奈瑟菌 ,总检出率为 5 .4 6 %。男性检出 9株 ,检出率 4 .4 6 % ,女性检出 13株 ,检出率为 6 .4 7%。其血清分型为 A群 3株 ,B群 14株 ,C群 2株 ,1892型 1株 ,未定型 2株。 2～ 4岁组检出 6株 ,检出率 8.5 7% (6 /70 ) ;6～ 8岁组检出 4株 ,检出率 7.4 1% (4/5 4 ) ;9～ 12岁组检出 6株 ,检出率8.0 0 % (6 /75 ) ;2 5～ 39岁组检出 6株 ,检出率 2 .94 % (6 /2 0 4 )。男女性别之间及少年不同组别正常人群鼻咽部脑膜炎奈菌携带率经 X2 检验差异均无显著性 ,而少年组与成人组比较相差有显著性意义。结论 :调查显示 ,本地区正常人群鼻咽部脑膜炎奈瑟菌携带率为 5 .4 6 % ,处于较低水平。血清分型以 B群为主 ,本地为非流行株。不同性别正常人群鼻咽部脑膜炎奈瑟菌的携带率无差别 ,儿童携带率较成人高。调查结果显示本地区目前不具备流行特点 ,A群脑膜炎奈瑟菌未造成本地流行性?
Objective:The aim of this study was to determine the prevalence of healthy Neisseria Meningitidis pharyngeal carriers in a representative sample of in zhongshan city.To provide scientist basis for government to control and prevent epidemic cerebrospinal miningitidis.Methods:The sample was divided into age groups:2～4,6～8,9～12 and 25～39 years old.Oropharyngeal swabs were collected with a cotton tipped swab in an Amies transport medium and cultured on Thayer Martin plates at 35 degrees C in 6% CO2 by 《native clinical laboratory technology rule》.The isolates were serogrouped and sero/subtyped.Results:Of the 403 persons studied ,22(5.46%)meningococcal carriers were detected:14 B(3.47%),3 A(0.74%),2 C(0.50%),2non grounp(0.50%),1 1892(0.25%).Conclusion:The prevalence of healthy carriers of N.meningitides in the popuation was 5.46%,being higher in the children age group.There are nostatistically significant differences among the different children age groups nor between sexes.Very low prevalence of serogroup A.No serogrounp D/W 135 meningococci were found in this study.Impossible to conclude that the strain N.meningitides serogroup A was circulaitng during the Spring,2002.
出处
《中国微生态学杂志》
CAS
CSCD
2002年第4期221-222,共2页
Chinese Journal of Microecology
