摘要
目的 :观察琥珀酰明胶注射液 (佳乐施 )对手术前急性超容性血液稀释 (AHHD)病人的MAP、CVP、HR、SpO2 、凝血机制以及尿量的影响和血液保护的实施。方法 :选择ASAⅠ～Ⅱ级全麻手术病人 40例 ,于输注佳乐施前 ,输液后10、2 0、3 0、60min记录MAP、CVP、HR、SpO2 和次日取深静脉血分别测定红细胞压积 (Hct)、血小板 (PLt)、血红蛋白(Hb)、凝血酶原时间 (PT)、部分凝血酶原时间 (APTT)并观察有无过敏反应 ,进行统计学处理。结果 :接受AHHD的病人 ,MAP、HR、CVP、尿量等在输注佳乐施后 10、2 0min比输注前均增加 (P <0 0 1,SpO2 无变化 ,3 0及 60min后渐恢复到输注前水平 (P >0 0 1) ,Hb、Hct、PLt均比AHHD前低 (P <0 0 1) ,PT、APTT均在正常范围内 (P >0 0 1)。结论 :用琥珀酰明胶注射液施行AHHD后病人的上述指标波动在正常范围内 ,说明术前对病人行AHHD是可行的 ,也是麻醉手术中治疗和预防低血压时替代血液的理想药品。
Objective Observe the effect of Gelofusine to MAP,CVP,HR,SpO 2,clotting mechanism?urine volume and blood protection of the patients who received preoperative acute hypervolemic hemodilution.Methods Forty patients'(ASA Ⅰ～Ⅱ)MAP?CVP?HR?SpO 2 were recorded at ten minutes,twenty minutes,thirty minutes and sixty minutes following the transfusion of Gelofusine.In the next day,taken the blood samples of the patients and mensurated Hct,PLt,Hb,PT,APTT. Results The MAP,CVP,HR and urine volume of the patients who received the transfusion of Gelofusine were increased at ten minutes and twenty minutes after the transfusion(P<0 01),and decreased gradually at thirty minutes and sixty minutes after the transfusion(P>0 01)and there weren't any change of SpO 2.The patients'Hb,Hct,PLt were depressed(P<0 01),but PT,APTT were in normal range(P>0 01).Conclusions The patients'MAP,CVP,HR and urine volume were in normal range after the use of Gelofusine in acute hypervolemic hemodilution.Gelofusine can reduce the use of blood transfusion.It can be used in acute hypervolemic hemodilution properly.In prevention and treatment of hypotension and emergency treatment of shock,Gelofusine can be used instead of blood.
出处
《中原医刊》
2002年第9期1-2,共2页
Central Plains Medical Journal
