摘要
目的:研究肺癌患者和肺结核患者及健康人血清中血管内皮生长因子(vascular endothelial growth factor,VEGF)水平,分析其临床意义,可望检测血清中VEGF能成为对肺癌诊断和鉴别诊断的指标之一。方法:采用酶联免疫吸附法(ELISA)定量检测40例肺癌患者、20例健康人、20例肺结核患者血清中血管内皮生长因子,并结合临床资料进行分析。结果:肺癌患者血清中VEGF含量与健康人、肺结核患者相比差异有统计学意义(P<0.001)。结论:肺癌患者血清中血管内皮生长因子(VEGF)水平明显高于健康人和肺结核患者,血清VEGF是有助于肺癌诊断及与肺结核鉴别诊断的一项有效指标。
Objective:This study was designed to investigate and compare the concentration of serum VEGF in lung cancer patients, normal controls, pulmonary tuberculosis patients.By analyzing its clinical significance,we hoped it could be a marker for the diagnosis and differential diagnosis of lung cancer.Methods:The study included 40 lung cancer patients,20 normal controls,20 pulmonary tuberculosis patients.Detecting the concentration of serum VEGF by ELISA.Results:Significant difference was found in the levels of serum VEGF between lung cancer patients and normal controls,pulmonary tuberculosis patients(P <0.001).Conclusion:The level of serum VEGF in lung cancer patients is higher than normal controls and pulmonary tuberculosis.It can be an assistant marker for the diagnosis of lung cancer and contribute to the differential diagnosis between lung cancer and pulmonary tuberculosis.
出处
《临床医药实践》
2009年第10Z期656-658,共3页
Proceeding of Clinical Medicine
关键词
肺癌
肺结核
健康人
血管内皮生长因子
Lung cancer
Pulmonary tuberculosis
Normal control
Vascular endothelial growth factor
