摘要
目的:探讨新生儿窒息对胃食管返流(GER)的影响。方法:用便携式24 h pH记录仪动态监测30例不同程度窒息后新生儿和15例对照新生儿的24 h食管pH值。结果:窒息组胃食管返流的各项参数均明显高于对照组,其中返流指数窒息组/对照组为7.8/1.9,返流次数为139/31,返流>5 min的次数6.1/0.9,pH<4总时间162/21,差异均有非常显著意义(P<0.01)。重度窒息组各项返流指数明显低于轻度窒息组和对照组(P<0.01)。结论:新生儿窒息可引起胃肠运动功能紊乱,窒息后新生儿胃食管返流较对照组明显增加,应及时给予相应的处理。
Objective: To investigate the effects of perinatal asphyxia on gastroesophageal reflux (GER) of the newborn. Methods: The distal 24 h esophageal pH monitoring was performed in 30 asphyxiated full term newborns and 17 controls using a Synectics Dig trapper System for ambulatory pH recording. Results: The 24 h esophageal pH monitoring revealed that the variables of acid reflux in asphyxia group were ail dramatically higher than those of controls. The reflux index was 7.8/1.9 (asphyxia group/control group), the number of reflux episodes was 139/31, the number of reflux over 5 rain was 6.1/0.9, the long time of reflux was 25.1/4.5, the total time of pH<4 were 162/21. The differences were all significant (P<0.01). The variables of reflux in the severe asphyxia group were all dramatically lower than those in the slight asphyxia group and controls (P<0.01). Conclusion: By the help of esophageal 24 h pH monitoring, the authors can get information about gastroenteric motility of asphyxia neonates. The gastroesophageal refux increased in the asphyxia neonates, early intervention should be given.
出处
《中国妇幼保健》
CAS
2004年第5X期90-91,共2页
Maternal and Child Health Care of China
关键词
窒息
新生儿
胃食管返流
氢离子浓度
Asphyxia
Neonate
Gastroesophageal reflux
Hydrogen-ion concentration
