摘要
目的:探讨阿伦磷酸钠治疗老年骨质疏松的临床效果。方法:选取2015年1月至2016年1月期间江西省上饶县人民医院收治的老年骨质疏松患者85例作为研究对象,将患者随机分为对照组和观察组两组,对照组42例给予钙尔奇D治疗,观察组43例则在对照组治疗基础上给予阿伦膦酸钠治疗。结果:治疗前两组患者腰椎、股骨颈、股骨粗隆、股骨等部位骨密度和疼痛VAS评分比较无显著差异(P>0.05),治疗后两组患者不同部位骨密度均有一定改善,观察组各部位骨密度显著高于对照组,疼痛VAS评分则显著低于对照组,差异均具有统计学意义(P<0.05)。两组患者不良反应发生情况比较无显著差异(P<0.05)。结论:阿仑膦酸钠治疗老年骨质疏松效果显著,患者疼痛症状可有效缓解,可在临床中推广应用。
Objective: To explore the clinical effect of Allen sodium phosphate in the treatment of senile osteoporosis. Methods: 85 elderly patients with osteoporosis in People's Hospital of Shangrao County between January 2015 and January 2016 were selected as the study subjects, and randomly divided into control group and observation group, with 42 cases in control group given Caltrate D treatment, and 43 cases of the observation group treated with Allen alendronate. Results: Before treatment, there was no significant difference between the two groups of patients with lumbar spine,femoral neck, femoral intertrochanteric, femoral and other parts of bone density and pain VAS score (P>0.05), however, the bone mineral density at different parts of the two groups were significantly improved after treatment. The bone density in the observation group was significantly higher than that in the control group. The pain VAS score was significantly lower than that in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P<0.05). Conclusion: The effect of the treatment of osteoporosis in the elderly is significant,the pain symptoms can be effectively alleviated, thus, it should be widely used in clinical practice.
作者
程伟峰
CHENG Wei-feng(People's Hospital of Shangrao County, Jiangxi Shangrao 334100, China)
出处
《药品评价》
CAS
2017年第1期29-31,共3页
Drug Evaluation
关键词
阿仑膦酸钠
老年
骨质疏松
疗效
Alendronate Sodium
Osteoporosis
Curative Effect
