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耳屏软骨环—软骨膜在鼓膜大穿孔修补的应用及影响其远期疗效相关因素分析 被引量:9

Tragus Cartilage Ring-Perichondrium Graft in Repair of Large Tympanic Membrane Perforation and Factors Affecting Long-Term Outcomes
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摘要 目的探讨耳屏软骨环—软骨膜在鼓膜大穿孔修补中的应用,并对影响其远期疗效的相关因素进行分析。方法 2004年1月~2013年12月在我院行耳屏软骨环—软骨膜鼓膜成形术的325例(375耳)患者的临床资料进行分析;观察指标:年龄,病程,干耳时间,术前气导听阈,术后骨导听阈,鼓室粘膜状况,鼓室硬化灶,听骨重链病变,咽鼓管功能,术中创面渗血;随访3年以上,用SPSS 16.2软件进行χ2检验和多元线性回归分析,以P<0.05为差异有统计学意义。结果本组病例年龄11~62岁,平均(36±8.32)岁,病程1年至36年,平均(21±7.62)年;1年鼓膜愈合率为94.8%,3年愈合率为91.6%;其影响手术效果的因素,经多因素分析其作用依次为:鼓室硬化斑灶,术前气导听阈,术前骨导听阈,病程,咽鼓管功能,术中创面渗血具相关性。结论影响耳屏软骨环—软骨膜鼓室成形术成功率的因素有:鼓室硬化灶、病程长短、咽鼓管功能有关、术前气骨导听阈损失状况,术中创面渗血明显也影响手术效果。 To report repair of large tympanic membrane perforation using tragus cartilage ring-perichondrium grafts and factors that can affect the long-term outcomes.Methods From January 2004 to December 2013,tragus Cartilage ring perichondrium grafts were used during myringoplasty in 325 patients(375 ears).Their clinical data,including age,duration of dry ear,preoperative air conduction hearing threshold,postoperative bone conduction hearing threshold,tympanic mucosa condition,tympanosclerosis lesions,ossicular chain lesion,Eustachian tube function,intraoperative blood oozing and follow-up data(more than 3 years),were analyzed using the SPSS 16.2 software.χ2 test and multiple linear regression analysis were employed with P<0.05 being statistically significant.Results The mean age of our patients was 36±8.32(11-62)years and the average disease duration was 21±7.62(1-36)years.The rate of tympanic membrane healing was 94.8%at 1 year and 91.6%at 3 years.Multivariate analysis of factors influencing operation results indicated correlation to the following:tympanosclerotic plaque lesions,preoperative air conduction hearing threshold,preoperative bone conduction hearing threshold,duration of disease,eustachian tube function and intraoperative blood oozing.Conclusion Tympanosclerotic plaque lesions,preoperative air conduction hearing threshold,duration of disease,eustachian tube function and intraoperative blood oozing appear to affect the efficacy of tympanoplasty using tragus cartilage ring-perichondrium grafts.
作者 刘雄光 姚立平 吴昌林 叶小武 吴海峰 唐甜甜 王雯 LIU Xiongguang;YAO Liping;WU Changlin;YE Xiaowu;WU Haifeng;TANG Tiantian;WANG Wen(Department of Otolaryngology,Ninth Affiliated Hospital,Guangxi University of Medical Sciences,Guangxi Beihai 536000,China)
出处 《中华耳科学杂志》 CSCD 北大核心 2018年第1期54-60,共7页 Chinese Journal of Otology
基金 广西北海市科技攻关项目(北科合201604001)~~
关键词 耳屏软骨环—软骨膜 鼓膜大穿孔 鼓室成形术 远期疗效 多元线性回归分析 The Tragus Cartilage Ring-Perichondrium Large Perforation of Tympanic Membrane Tympanoplasty Long-Dated Curative Effect Multiple Linear Regression Analysis
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