摘要
目的:观察抑抗方对于免疫因素所致不孕不育患者的疗效、妊娠结局以及对患者性激素分泌水平的影响。方法:选取82例免疫性不孕不育患者作为本次研究资料,将全部入选患者分别纳入对照组与观察组,对照组行常规治疗,观察组在于常规治疗的基础上加用自拟抑抗方治疗;治疗1疗程后评估两组临床疗效,观察两组治疗前、后性激素指标:卵泡生成激素(FSH)、黄体生成激素(LH)、雌二醇(E_2)、睾酮(T)、催乳激素(PRL)表达水平的变化,全部患者随访6个月统计成功妊娠率,对于成功妊娠的患者随访期延长至妊娠结束,统计成功分娩率。结果:对照组总有效率73.17%,观察组总有效率95.12%,观察组更为理想(P<0.05);治疗后观察组FSH、E_2、T分泌水平优于对照组(P<0.05);观察组成功妊娠率80.49%、成功分娩率78.05%,对照组成功妊娠率53.66%、成功分娩率43.90%,观察组更为理想(P<0.05)。结论:自拟抵抗方对于免疫因素所致不孕不育患者具有明确疗效,可改善患者FSH、PRL等性激素指标,因此能够有效提高成功妊娠率与成功分娩率。
Objective:To observe the effect of Yikang decoction on the efficacy,pregnancy outcome and sexual hormone secretion of infertility patients caused by immune factors.Methods:82 cases of immune infertility patients as the data in this study,all patients were divided into control group and observation group,the control group received routine treatment,the observation group was treated with self-made Yikang decoction in the treatment of two groups of clinical curative effect evaluation of treatment;after a period of treatment,two groups were observed before and after the treatment of sex hormone index:follicle stimulating hormone(FSH)and luteinizing hormone(LH),estradiol(E 2),testosterone(T),prolactin(PRL)levels in all patients were followed up for 6 months for patients with successful pregnancy rate statistics.The follow-up period of successful pregnancy was extended to the end of pregnancy,successful delivery rate statistics.Results:In the control group,the total efficiency of 73.17%,the total efficiency of the observation group 95.12%,observation group was more ideal(P<0.05);after treatment in observation group,FSH,E 2 and T levels than the control group,the observation group P<0.05;successful pregnancy rate was 80.49%,the successful delivery rate was 78.05%,the control group of successful pregnancy rate 53.66%,successful delivery rate was 43.90%,the observation group was more ideal(P<0.05).Conclusion:Yikang decoction has a definite effect on infertility caused by immune factors,and can improve the FSH,PRL and other sex hormones.Therefore,it can effectively improve the successful pregnancy rate and the successful delivery rate.
作者
曹雪梅
张洛琴
邓文风
申爱荣
Cao Xuemei;Zhang Luoqin;Deng Wenfeng(Gynaecology and Obstetrics Department of Sanmenxia Traditional Chinese Medicine Hospital(Sanmenxia 472000))
出处
《陕西中医》
2018年第5期605-607,共3页
Shaanxi Journal of Traditional Chinese Medicine
基金
河南省医学科技攻关计划项目(424410031)
关键词
不育
女性/中医药疗法
卵泡刺激素
@抑抗方
Infertility,female/traditional Chinese medicine therapy
Follicle stimulating hormone
@Yikang decoction
