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星空现象在肿瘤中的病理意义

Pathological significance of the starry sky pattern in tumors
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摘要 "星空现象"是巨噬细胞吞噬细胞残存和核碎片后而产生的一种病理组织学现象,也是机体淋巴组织和淋巴瘤中一个独特的组织学特征。本文对"星空现象"的发展史、发生机制、病理生理和临床特征做一总结和综述。希望对建立淋巴肿瘤动物模型以及放疗药物对患肿瘤动物在临床肿的研究、药物治疗剂量的选择有一定帮助和参考意义。 The starry sky pattern is a distinctive histological feature in lymphoid tissue and lymphoma.The cytoplasm of these histiocytes typically contains cellular remnants.Here,this review discusses the historical,pathophysiological and pathophysiological research of the starry sky pattern,which may contribute to establishment of a lymphoma animal model,development of radiation and drug therapies,and determination of doses.
作者 赵文杰 秦川 ZHAO Wenjie;QIN Chuan(Institute of Laboratory Animal Sciences,Chinese Academy of Medical Sciences(CAMS);Comparative Medicine Center,Peking Union Medical College(PUMC);Key Laboratory of Human Disease Comparative Medicine,National Health and Family Planning Commission of the People’s Republic of China(NHFPC);Key)
出处 《中国比较医学杂志》 CAS 北大核心 2018年第7期118-123,共6页 Chinese Journal of Comparative Medicine
关键词 星空现象 淋巴瘤 动物模型 巨噬细胞 starry sky pattern lymphoma animal models macrophage
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