摘要
目的探讨药物不良反应(ADR)发生特点和规律,为促进临床合理用药和改善护理ADR监测工作提供指导依据。方法采用回顾性分析方法,对湖北省孝感市中心医院、十堰市人民医院、荆州市第一人民医院共3家三级综合医院上报的1070例ADR报告资料进行整理和分析。结果 1070例ADR报告中,≥60岁患者ADR发生较多(367例,34.30%);静脉滴注ADR发生率最高(689例,64.39%);严重ADR共计48例(4.49%);涉及药品205种,其中抗感染用药引起ADR最多(785例次,55.83%),其次为中药及中药制剂(214例次,15.22%);ADR临床表现多样,以皮肤及附件损害最多(563例次,46.99%)。结论 ADR的发生与诸多因素相关,应重点关注ADR易发药物和人群,选择合适的给药途径,并密切关注患者情况,充分发挥护士监测作用,以不断促进ADR监测和护理工作的持续改进。
Objective To explore the characteristics and regularity of adverse drug reaction(ADR),and to provide guidance for promoting clinical rational drug use and improving nursing ADR monitoring.Methods A retrospective analysis method was used to analyze the data of 1070 ADR reports collected in Xiaogan central hospital,Shiyan people′s hospital and Jingzhou first people′s hospital in Hubei province.Results In 1070 ADR cases,patients≥60 years got more ADR(367,34.30%);intravenous infusion got the most(689 cases,64.39%);severe ADR was 48 cases(4.49%);all ADRs involving 205 kinds of drugs and anti-infection drugs caused the most ADR(785,55.83%),followed by traditional Chinese medicine and Chinese medicine preparations(214,15.22%);the clinical manifestations in ADR were varied,with the most damage to skin and accessories(563,46.99%).Conclusion The occurrence of ADR is related to many factors,focusing on ADR susceptible drug and population,choosing the appropriate way to administer the drugs,paying close attention to the patient′s situation,and making full use of nurse ADR monitoring function to continuously promote the quality of ADR monitoring and nursing work.
作者
刘玉
魏威
宋勇波
LIU Yu;WEI Wei;SONG Yongbo(Department of Critical Care Medicine,Xiaogan Central Hospital,Hubei Province,Xiaogan 432000,China;Central Laboratory,Xiaogan Central Hospital,Hubei Province,Xiaogan 432000,China;Department of Urology Surgery,Xiaogan Central Hospital,Hubei Province,Xiaogan 432000,China)
出处
《中国医药导报》
CAS
2018年第21期174-177,共4页
China Medical Herald
关键词
药物不良反应
合理用药
护理
回顾性分析
对策
Adverse drug reaction
Rational drug use
Nursing
Retrospective analysis
Countermeasures
