摘要
目的:探讨磁共振扩散加权成像对慢性胰腺炎及胰腺癌的诊断价值。方法:选取笔者所在医院2015年1月-2017年12月收治的49例慢性胰腺炎患者,49例胰腺癌患者,再选择正常健康人49例作为对照组。受试者均行上腹部规律扫描后磁共振扩散加权成像,对比慢性胰腺炎患者,胰腺癌患者及健康正常人组T1WI、T2WI信号强度和组织表观扩散系数值,评价磁共振扩散加权成像的诊断价值。结果:当b=0.600 s/mm2及b=0.100 s/mm2时,慢性胰腺炎组患者表观扩散系数值范围为1.597~2.023和1.330~1.792,而胰腺癌组范围分别为0.155~2.467和0.975~1.391。胰腺癌组表观扩散系数值明显低于其余两组,且慢性胰腺炎组表观扩散系数值显著低于正常对照组,差异均有统计学意义(P<0.05)。胰腺癌组在T1WI上呈低信号,T2WI上呈稍高信号,DWI上呈高信号。DWI信号强度高于T1WI和T2WI,差异有统计学意义(t=9.33、6.01,P<0.05),而T1WI和T2WI间则无统计学意义(t=1.94,P>0.05)。结论:磁共振扩散加权成像扫描具有辅助鉴别诊断慢性胰腺炎及胰腺癌的作用。
Objective:To evaluate the diagnostic value of diffusion-weighted magnetic resonance imaging in chronic pancreatitis and pancreatic cancer.Method:A total of 49 patients with chronic pancreatitis and 49 cases with pancreatic cancer treated in the author’s hospital from January 2015 to December 2017 were selected,49 cases of normal healthy persons were selected as the control group.All subjects were performed on abdominal law after scanning magnetic resonance diffusion weighted imaging.The signal intensity and apparent diffusion coefficient of T1WI and T2WI were compared among patients with chronic pancreatitis,patients with pancreatic cancer and healthy controls.The diagnostic value of diffusion-weighted magnetic resonance imaging(DWI)were evaluated.Result:When b=0.600 s/mm2 and b=0.100 s/mm2,the apparent diffusion coefficient value in the patients in the chronic pancreatitis group were 1.597-2.023 and 1.330-1.792,while the pancreatic cancer group was 0.155-2.467 and 0.975-1.391 respectively.The apparent diffusion coefficient in pancreatic cancer group was significantly lower than that in the other two groups,and the apparent diffusion coefficient value in chronic pancreatitis group was significantly lower than that in normal control group,the differences were statistically significant(P<0.05).The pancreatic cancer group showed low signal intensity on T1WI and slightly high signal intensity on T2WI and high signal intensity on DWI.The signal intensity of DWI was higher than that of T1WI and T2WI.The difference was statistically significant(t=9.33,6.01,P<0.05),but there was no significant difference between T1WI and T2WI(t=1.94,P>0.05).Conclusion:Magnetic resonance diffusion weighted imaging scans have the function of the auxiliary differential diagnosis of chronic pancreatitis and pancreatic cancer.
作者
李姗
LI Shan(The First People’s Hospital of Shuangliu District in Chengdu City,Chengdu 610200,China)
出处
《中外医学研究》
2018年第20期65-67,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
磁共振扩散加权成像
慢性胰腺炎
胰腺癌
诊断价值
Magnetic resonance diffusion weighted imaging
Chronic pancreatitis
Pancreatic cancer
Diagnosis value
