摘要
目的研究血清降钙素原(PCT)及白细胞计数(WBC)水平对骨折并发脓毒血症患儿预后的临床评估价值。方法研究选取徐州市儿童医院2017年4月—2017年12月经ICU收治的72例骨折并发脓毒血症患儿,根据其病情发展结果分为生存组(43例)和死亡组(29例)。探讨血清PCT和WBC水平与ICU骨折并发脓毒血症患儿的预后关系及其临床应用价值。结果两组患儿在1、3d的血清PCT和WBC计数水平差异均无统计学意义(P> 0. 05),在5、7d的血清PCT和WBC计数水平差异均具有统计学意义(P <0. 05),两指标的检测水平在生存组均显著低于死亡组(P <0. 05)。患者血清PCT、WBC的灵敏度和特异度分别为74. 4%、72. 4%和67. 4%、69. 0%,PCT和WBC具有一定的预测患儿预后情况的价值。结论血清PCT与WBC计数水平可以有效评估ICU骨折并发脓毒血症患儿的预后情况,PCT浓度和WBC计数水平越高,预后越差,可作为预后情况的临床预测指标。
Objective To investigate the effect of serum procalcitonin(PCT)and white blood cell levels(WBC)in evaluating prognosis of children with fracture and sepsis.Methods Seventy-two children with fractures and sepsis admitted to the ICU of Xuzhou Children s Hospital from Apr.2017to Dec.2017were selected.According to the results of the disease development,they were divided into the survival group(43cases)and the death group(29cases).The effect of serum PCT and WBC on prognosis of children with fracture and sepsis and their clinical application value were explored.Results There was no significant difference in serum PCT and WBC levels between the two groups on day1and day3(P>0.05).There were significant differences in serum PCT and WBC levels on day5and day7(P<0.05),and the levels of PCT and WBC in the survival group were significantly lower than those in the death group.The sensitivity and specificity of patients serum PCT and WBC were74.40%,72.40%,and67.40%,69.00%,respectively.PCT and WBC had ralue in evaluating the prognosis of children with fracture and sepsis.Conculsion The serum PCT and WBC levels can effectively evaluate the prognosis of children in ICU with fracture and sepsis.The higher the PCT concentration and WBC level are,the worse the prognosis is,which can be used as a clinical predictor of prognosis.
作者
曹军华
田礼军
季强
张传玲
钱同
CAO Jun-hua;TIAN Li-jun;JI Qiang;ZHANG Chuan-ling;ZHANG Chuan-ling(Department of Laboratory Science,Xuzhou Children s Hospital,Xuzhou,Jiangsu 221006,China)
出处
《创伤外科杂志》
2018年第12期933-935,共3页
Journal of Traumatic Surgery
