摘要
目的探讨对急诊重度脑外伤并休克患者实施高渗盐液治疗的效果。方法随机将我院100例急诊重度脑外伤并休克患者分为观察组(50例,应用高渗盐液治疗)、对照组(50例,应用甘露醇溶液治疗)。对比两组患者的平均动脉压(MAP)、心率(HR)、颅内压(ICP)、脑灌注压(CPP)、尿量(UPD)、有效率、病死率、住院时间及住院总费用。结果观察组患者治疗2h MAP和对照组无显著差异,P> 0.05,但HR[(102.34±4.61)次/min]相比对照组明显更低,P <0.05;观察组患者治疗后ICP[(26.35±1.78)mL]、UPD[(52.34±13.61)mL]相比对照组明显更少,P <0.05,且CPP相比对照组明显更高,P <0.05;观察组患者有效率(98.00%)相比对照组(84.00%)明显更高,病死率(2.50%)相比对照组(16.00%)明显更低,P <0.05;观察组住院时间及住院总费用较对照组明显更少,P <0.05。结论对急诊重度脑外伤并休克患者实施高渗盐液治疗十分可行,有助于提高抢救效果。
Objective To explore the effect of hypertonic saline in emergency treatment of severe brain trauma combined with shock.Methods100cases with severe brain trauma combined with shock in our hospital were randomly divided into the observation group(50cases,treated by hypertonic saline)and the control group(50cases,treated by mannitol solution).Mean arterial pressure(MAP),heart rate(HR),intracranial pressure(ICP),cerebral perfusion pressure(CPP),urine output(UPD),effectiveness,mortality,length of hospital stay,and total hospitalization cost in the two groups were compared.Results There was no significant difference between the observation group and the control group for MAP2h treatment,P>0.05.HR[(102.34±4.61)times/min]in the observation was significantly lower than the control group,P<0.05.After treatment,ICP[(26.35±1.78)mL]and UPD[(52.34±13.61)mL]in the observation group were significantly less than the control group,P<0.05,and CPP was significantly higher than the control group,P<0.05.The effective rate of the observation group(98.00%)was significantly higher than the control group(84.00%),and the mortality rate(2.50%)was significantly lower than the control group(16.00%),P<0.05.The hospitalization time and total hospitalization expenses of the observation group were significantly less than the control group,P<0.05.Conclusion It is feasible to treat severe brain trauma patients combined with shock by hypertonic saline,which is helpful to improve the rescue effect.
作者
何大勇
王棣祥
王春华
刘淑兰
HE Dayong;WANG Dixiang;WANG Chunhua;LIU Shulan(Pangang Group General Hospital of Panzhihua City, Sichuan Province, Panzhihua 617000, China)
出处
《中国医药科学》
2018年第21期182-184,205,共4页
China Medicine And Pharmacy
关键词
急诊
重度脑外伤
休克
高渗盐液
Emergency treatment
Severe brain trauma
Shock
Hypertonic saline
