摘要
目的探讨抗生素降阶梯疗法对新生儿重症感染性肺炎的治疗效果。方法选取重症感染性肺炎新生儿120例,分为观察组(抗生素降阶梯疗法)与对照组(常规经验性抗生素治疗),比较2组患儿的临床治疗效果。结果观察组患儿肺部湿啰音、发热、气促、发绀、呼吸困难等临床症状消失时间及住院时间均显著短于对照组(P <0. 05);治疗后,观察组患儿C反应蛋白、白细胞水平显著低于对照组(P <0. 05);观察组患儿治疗总有效率显著高于对照组(P <0. 05)。结论采用抗生素降阶梯疗法对新生儿重症感染性肺炎进行治疗,可及时控制患儿临床症状,提高抗感染效果,对保障患儿生命安全具有积极作用。
Objective To explore the clinical effect of antibiotic descending step therapy on neonatal severe infectious pneumonia.Methods A total of 120 neonates with severe infectious pneumonia admitted to our hospital were divided into observation group(antibiotic descending step therapy)and control group(regular empirical antibiotic treatment),the clinical treatment effects of the two groups were compared.Results The time of disappearance of clinical symptoms such as rales,fever,polypnea,cyanopathy and dyspnea in the observation group were significantly shorter than that of the control group(P<0.05).The C reactive protein level and white blood cell level of the observation group after treatment were significantly lower than that of the control group(P<0.05).The total treatment efficiency of the observation group was significantly higher than that of the control group(P<0.05).Conclusion Antibiotic step-down therapy for neonatal severe infectious pneumonia can timely control clinical symptoms of children,improve anti-infection effect,and safeguard children′s life safety.
作者
马英
乔晓霞
索磊
张惠芳
MA Ying;QIAO Xiaoxia;SUO Lei;ZHANG Huifang(Neonatal Department,Xi′an children′s Hospital,Xi′an,Shaanxi,710003)
出处
《实用临床医药杂志》
CAS
2019年第1期56-58,62,共4页
Journal of Clinical Medicine in Practice
基金
陕西省卫生厅科研基金项目(2016D01270)
关键词
新生儿
重症感染性肺炎
抗生素
降阶梯疗法
C反应蛋白
neonates
severe infectious pneumonia
antibiotics
step-down therapy
C reactive protein
