摘要
报道我科2017年收治的1例确诊组织细胞坏死性淋巴结炎(histiocytic necrotizing lymphadenitis,HNL)患者,并回顾分析164例文献报道经病理证实HNL患者的临床特点。HNL是一种良性自限性疾病,临床上以发热、痛性淋巴结肿大、白细胞减少为主要特征,其临床表现和实验室检查缺乏特异性,易误诊为恶性淋巴瘤、淋巴结炎、淋巴结结核、系统性红斑狼疮等。淋巴结活检病理检查可明确诊断,抗生素治疗无效,症状显著时应用糖皮质激素有效。因其可有多器官受损及可能并发自身免疫性疾病,故应尽早诊断及治疗并长期随访。现对该病的临床特点作一总结,以提高对本病的认识。
A confirmed case of histiocytic necrotizing lymphadenitis(HNL) was reported and 164 cases of pathologically confirmed HNL with clinical features were analyzed retrospectively. HNL is a benign and self-limited disease. It is characterized by fever,painful lymphadenopathy,and leukopenia in clinic. Its clinical manifestations and laboratory tests lack specificity and are easily misdiagnosed as malignant lymphoma, lymphadenitis, lymph node tuberculosis,and systemic lupus erythematosus. Lymph node biopsy for pathological examination can be used for the diagnosis. Antibiotic treatment is ineffective,and glucocorticoids is effective when symptoms are significant. Because it can be accompanied by multiple organ damages and may be associated with autoimmune disease,it should be diagnosed and treated as soon as possible and should be long-term followed-up. This paper summarized the clinical features of HNL in order to improve the understanding of the disease.
作者
江俊
孙媛
陈英
裴婷
张海利
JIANG Jun;SUN Yuan;CHEN Ying;PEI Ting;ZHANG Haili(the First Clinical Medical College of Shanxi Medical University,Taiyuan 030001,China)
出处
《中国眼耳鼻喉科杂志》
2019年第2期128-130,136,共4页
Chinese Journal of Ophthalmology and Otorhinolaryngology
关键词
组织细胞坏死性淋巴结炎
诊断
病理学
Histiocytic necrotizing lymphadenitis
Diagnosis
Pathology
