摘要
目的探讨精准肝切除术治疗肝细胞肝癌患者的近期疗效以及远期预后。方法对运城市中心医院2010年2月至2012年12月收治的120例肝细胞肝癌患者的临床资料进行回顾性分析。按照不同治疗方式将患者分成观察组与对照组,每组60例。观察组患者采用精准肝切除术治疗,对照组患者采用传统手术治疗。观察两组患者的临床疗效以及远期预后。结果观察组患者手术时间、术中出血量、围术期输血量、围术期输血率、Pringle法比例、血流阻断时间、并发症发生率以及术后住院时间均低于对照组(P<0.05),而两组患者再次手术率比较差异未见统计学意义(P>0.05);观察组患者肿瘤直径大于对照组(P<0.05),而肿瘤数目、子灶、肿瘤类型、门脉癌栓、包膜、肿瘤分化程度比较差异未见统计学意义(P>0.05);两组患者共随访5年,对照组58例与观察组57例患者获得随访,随访率为95.83%。观察组患者3、5年生存率高于对照组(P<0.05),而1年生存率两组患者比较差异未见统计学意义(P>0.05)。结论精准肝切除术治疗肝细胞肝癌能减少手术时间、术中出血量以及并发症发生率,具有较高的临床疗效,且能改善患者预后,延长患者生存时间。
Objective To investigate the short term efficacy and long-term prognosis of precise hepatectomy in the treatment of patients with hepatocellular carcinoma.Methods The clinical data of 120 patients with hepatocellular carcinoma treated in Yuncheng Central Hospital from February 2010 to December 2012 were retrospectively analyzed.According to different treatment methods,the patients were divided into observation group and control group,with 60 cases in each group.The patients in the observation group were treated with precise hepatectomy,and the patients in the control group were treated with traditional surgery.The clinical effect and long-term prognosis of the two groups were observed and compared.Results The operative time,blood loss,perioperative blood transfusion,perioperative blood transfusion rate,Pringle ratio,blood flow occlusion time,complication rate and postoperative hospitalization time in the observation group were significantly lower than those in the control group(P<0.05),and the reoperation rate in the two groups was not significantly different(P>0.05).The tumor diameter in the observation group was significantly higher than that in the control group(P<0.05),but the number of tumors,sub stove,tumor type,tumor thrombus in the portal vein,capsule and tumor differentiation were not significantly different(P>0.05).The two groups were followed up for a total of 5 years.There were 58 cases in the control group and 57 cases in the observation group were followed up,and the follow-up rate was 95.83%.The survival rate of the observation group at 3 and 5 years was significantly higher than that of the control group(P<0.05),but there was no significant difference between the two groups in the 1-year survival rate(P>0.05).Conclusions The precise hepatectomy for hepatocellular carcinoma can significantly reduce the time of operation,the amount of bleeding during operation and the incidence of complications,which has high clinical efficacy.It can improve the prognosis of patients and the survival time of patients.
作者
姚鹏
王秀丽
Yao Peng;Wang Xiuli(Department of Hepatobiliary Surgery,Yuncheng Central Hospital,Yuncheng 044000,China;Department of Infectious Diseases,Yuncheng Central Hospital,Yuncheng 044000,China)
出处
《中国实用医刊》
2019年第2期89-92,共4页
Chinese Journal of Practical Medicine
关键词
精准肝切除术
肝细胞肝癌
近期疗效
远期预后
传统手术
Precise hepatectomy
Hepatocellular carcinoma
Recent curative effect
Long term prognosis
Traditional operation
