摘要
目的比较内镜下黏膜切除术(EMR)、内镜下黏膜剥离术(ESD)对早期消化道肿瘤的治疗效果。方法回顾性分析运城市中心医院2015年9月至2018年8月收治的240例早期消化道肿瘤患者的临床资料,按手术方式分为EMR组和ESD组。EMR组200例,行内镜下黏膜切除术;ESD组40例,行内镜下黏膜剥离术。比较两组一般手术情况及手术效果。结果ESD组手术时间长于EMR组[(67.21±11.35)min比(39.32±6.67)min],P<0.05;两组术后住院时间比较,差异未见统计学意义(P>0.05);ESD组术后病灶残留率(5.0%)少于EMR组(32.5%),差异有统计学意义(P<0.05);ESD组随访疾病复发率为2.5%,EMR组为0,两组比较差异未见统计学意义(P>0.05)。结论临床医生应准确掌握EMR、ESD的相关适应证,接诊早期消化道肿瘤患者时需根据其实际情况选择合适的内镜下手术治疗方案,从而有利于保障其疗效及预后。
Objective To compare the therapeutic effects between endoscopic mucosal dissection (ESD) and endoscopic mucosal resection (EMR) on early digestive tract tumors. Methods The clinical data of 240 patients with early gastrointestinal cancer admitted to Yuncheng Central Hospital from September 2015 to August 2018 were retrospectively analyzed. Patients were divided into EMR group and ESD group according to operation methods. Two hundred patients in EMR group underwent endoscopic mucosal resection and 40 patients in group ESD underwent endoscopic mucosal dissection. The operation condition and operative effect of the two groups were compared. Results The operation time of ESD group was significantly longer than that of EMR group,(67.21±11.35)min vs.(39.32±6.67)min, P<0.05. There was no significant difference in postoperative hospital stay between the two groups (P>0.05). The residual rate of lesions after operation in ESD group (5.0%) was lower than that in EMR group (32.5%), P<0.05. The recurrence rate was 2.5% in ESD group and 0 in EMR group, and there was no significant difference between the two groups (P>0.05). Conclusions Clinicians should accurately master the indications for endoscopic mucosal resection and endoscopic mucosal dissection. After receiving early gastrointestinal cancer patients, it is necessary to select appropriate endoscopic surgical treatment according to their individual conditions, which is beneficial to the guarantee of efficacy and prognosis.
作者
王艳芳
邵茉莉
杨黎黎
Wang Yanfang;Shao Moli;Yang Lili(Department of Gastroenterology, Yuncheng Central Hospital, Yuncheng 044000, China)
出处
《中国实用医刊》
2019年第1期91-93,共3页
Chinese Journal of Practical Medicine
关键词
早期消化道肿瘤
内镜下黏膜切除术
内镜下黏膜剥离术
临床应用价值
Early digestive tract tumors
Endoscopic mucosal resection
Endoscopic mucosal dissection
Clinical application value
