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白虎汤加减联合针灸治疗痰热腑实型卒中相关性肺炎的临床疗效以及对血清炎症因子的影响 被引量:20

Clinical Effect of Baihu Decoction Combined with Acupuncture and Moxibustion on Treatment of Phlegm-Heat Syndrome of Stroke-associated Pneumonia and Its Effect on Serum Inflammatory Factors
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摘要 目的:研究白虎汤加减联合针灸治疗痰热腑实型卒中相关性肺炎的临床疗效,并分析其对血清炎症因子水平的影响。方法:将2016年2月—2018年2月期间本院收治的痰热腑实型卒中相关性肺炎患者108例随机分成观察组与对照组,对照组采用抗生素治疗,观察组在对照组基础上联合白虎汤加减、针灸治疗。比较两组的临床疗效、症状缓解时间以及血清炎症因子水平。结果:观察组与对照组治疗后的临床总有效率分别为88. 89%以及73. 47%,观察组明显的高于对照组;观察组患者的退热时间、咳嗽缓解时间、肺部啰音消失时间以及住院时间均明显的短于对照组;治疗后,观察组的血清IL-6、TNF-α以及CRP水平显著的低于对照组;比较差异均具有显著性(P <0. 05)。结论:白虎汤加减联合针灸治疗卒中相关性肺炎促进了病情缓解,提高了临床疗效,降低了机体炎症反应,安全性好。 Objective: To study the clinical efficacy of Baihu Decoction combined with acupuncture and moxibustion in the treatment of phlegm-heat syndrome of stroke-associated pneumonia and analyze its effect on serum inflammatory factors. Methods: A total of 108 patients with phlegm-heat syndrome of stroke-associated pneumonia treated in our hospital from February2016 to February 2018 were randomly divided into observation group and control group. The control group was treated with antibiotics. The observation group was combined with Baihu Decoction and acupuncture and moxibustion on the basis of the control group. The clinical efficacy,symptom relief time and serum inflammatory factors were compared between the two groups. Results:The total clinical effective rate of the observation group and control group after treatment was 88. 89% and 73. 47%,respectively,which was significantly higher in the observation group than that in the control group. The time of fever withdrawal,cough remission,lung voice disappearance and hospital stay were observed in the observation group. All of them were significantly shorter than those of the control group. After treatment,serum IL-6,TNF-α and CRP levels in the observation group were significantly lower than those in the control group. The differences were all significant( P < 0. 05). Conclusion: Baihu Decoction and acupuncture and moxibustion of phlegm-heat syndrome of stroke-associated pneumonia promoted the remission of the disease,improved the clinical efficacy,reduced the body’s inflammatory response and had good safety.
作者 李德需 张丽妍 赵永辰 张占英 张彦广 张新文 LI Dexu;ZHANG Liyan;ZHA0 Yongchen;ZHANG Zhanying;ZHANG Yanguang;ZHANG Xinwen(Integrated TCM & Western Medicine Dept,The Affiliated Hospital of Hebei University,Baoding 071000,Hebei,China;Integrated TCM & Western Medicine Dept,The Seventh hospital of Baoding, Baoding 071000,Hebei,China)
出处 《辽宁中医杂志》 CAS 2019年第4期749-752,共4页 Liaoning Journal of Traditional Chinese Medicine
关键词 白虎汤 针灸 卒中相关性肺炎 炎症因子 Baihu Decoction acupuncture and moxibustion stroke-associated pneumonia inflammatory factors
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