摘要
目的探讨2型糖尿病患者下肢血管病变与肾脏损伤的关系。方法收集我院2016年2月—2018年1月2型糖尿病患者100例,根据患者是否发生下肢血管病变,分为研究组(发生下肢血管病变)和对照组(未发生下肢血管病变)。对比两组基本临床病史及实验室指标;两组尿肌酐水平;研究组中不同狭窄程度患者的尿肌酐水平。结果两组患者在糖尿病病程、高血压发病率、血脂异常率及吸烟率上差异有统计学意义(P<0.05);研究组的空腹血糖及餐后2小时血糖水平上明显高于对照组,差异有统计学意义(P<0.05);研究组尿肌酐水平大于对照组,差异有统计学意义(P<0.05);研究组中不同狭窄程度患者的尿肌酐水平存在差异,以严重狭窄者的尿肌酐水平最高,差异有统计学意义(P<0.05)。结论2型糖尿病患者下肢血管病变与肾脏损伤存在一定关系,随着下肢血管狭窄的加重,会增加肾脏损伤。
Objective To investigate the relationship between lower extremity vascular lesions and renal injury in type 2 diabetes mellitus.Methods 100 patients with type 2 diabetes mellitus from February 2016 to January 2018 in our hospital were divided into two groups according to whether they had lower extremity vascular disease:study group(lower extremity vascular disease)and control group(no lower extremity vascular disease).The basic clinical history and laboratory indicators of the two groups were compared.The levels of creatinine in urine of the two groups were compared.The levels of creatinine in urine of patients with different degrees of stenosis in the study group were compared.Results There were significant differences in course of diabetes,incidence of hypertension,abnormal blood lipid and smoking rate between the two groups(P<0.05);fasting blood glucose and 2-hour postprandial blood glucose levels in the study group were significantly higher than those in the control group(P<0.05);the level of urinary creatinine in the study group was higher than that in the control group(P<0.05);the difference was significant in the study group(P<0.05).The level of urinary creatinine in patients with severe stenosis was the highest(P<0.05).Conclusion There is a certain relationship between lower limb vascular lesions and renal injury in type 2 diabetes mellitus.With the aggravation of lower limb vascular stenosis,renal injury will increase.
作者
蔡林江
沈菊
CAI Linjiang;SHEN Ju(Department of Internal Medicine,The Fourth People's Hospital of Haimen City,Haimen Jiangsu 226141,China;Department of Ultrasound,The Fourth People's Hospital of Haimen City,Haimen Jiangsu 226141,China)
出处
《中国继续医学教育》
2019年第16期101-103,共3页
China Continuing Medical Education
关键词
2型糖尿病
下肢血管病变
肾脏损伤
肌酐
狭窄
type 2 diabetes mellitus
lower extremity vascular disease
renal injury
creatinine
stenosis
