摘要
目的比较左半结肠癌与右半结肠癌的临床及病理特征。方法选取920例结肠癌患者展开研究,其中左半结肠癌200例,右半结肠癌720例;比较左半结肠癌与右半结肠癌患者的性别、年龄、肿瘤组织类型、病理分级、浸润深度、淋巴结转移、远处转移情况等临床资料及病理特征。结果左、右半结肠癌组患者的性别、年龄、肿瘤组织类型、病理分级、浸润深度、神经/脉管浸润、淋巴结转移之间的差异均有统计学意义(均P<0.05),但两者的肿瘤大小、TNM分期、远处转移之间的差异均无统计学意义(均P>0.05)。左半结肠癌患者的中位生存期显著长于右半结肠癌患者(P<0.05),5年生存率显著高于右半结肠癌患者,差异有统计学意义(P<0.05)。结论右半结肠癌肿低分化与未分化腺癌及黏液腺癌较左半结肠多,浸润深度较左半结肠癌大,神经/脉管侵犯、淋巴结转移较左半结肠癌多,临床要及时对结肠癌实施筛查与诊断。
Objective To compare the clinicopathological features between left and right colon cancer.Methods Clinicopathological data of 920 patients with colon cancer,including 200 cases of left colon cancer and 720 cases of right colon cancer,admitted to our hospital from June 2005 to June 2013 were retrospectively analyzed.The tissue type,pathological grade,infiltration depth,lymph node metastasis and distant metastasis of the two groups were compared.Results There were significant differences in gender,age,tissue type,pathological grade,infiltration depth,nerve/vessel infiltration and lymph node metastasis between the left and right colon cancer groups(P<0.05),but there were no significant differences in tumor size,TNM staging and distant metastasis between the two groups(P>0.05).The median survival time of patients with left colon cancer was significantly longer than that of patients with right colon cancer(P<0.05),and the 5-year survival rate of patients with left colon cancer was significantly higher than of patients with right colon cancer(P<0.05).Conclusion There are more poorly differentiated and undifferentiated adenocarcinoma and mucinous adenocarcinoma in the right colon cancer than in the left colon cancer,and the infiltration depth is larger than that in the left colon cancer.Nerve/vessel invasion and lymph node metastasis are more than those in the left colon cancer.
作者
袁马驰
YUAN Machi(Department of Pathology,Hangzhou Third People’s Hospital,Hangzhou 310009,China)
出处
《浙江医学》
CAS
2019年第11期1191-1193,共3页
Zhejiang Medical Journal
关键词
左半结肠癌
右半结肠癌
病理
分析
Left hemicolon cancer
Right hemicolon cancer
Pathology
Analysis
