摘要
采用生物表面活性剂大豆分离蛋白(SPI)功能化修饰经酸化提纯的单壁碳纳米管(O-SWCNTs),得到纳米复合材料(SPI-O-SWCNTs)。对SPI-O-SWCNTs及其性能进行了测试和表征。透射电子显微镜(TEM)观察表明:SPI有效提高了O-SWCNTs的分散性。X射线光电子能谱(XPS)和拉曼光谱分析表明:SPI通过物理作用吸附到了O-SWCNTs表面,导致O-SWCNTs表面的C原子混乱度少许增加以及电化学性能降低。药物体外释放实验和细胞毒性检验实验表明:SPI修饰后的O-SWCNTs,能够提高药物的缓释效果,并且降低了对细胞的毒性。
Nanosized composites(SPI-O-SWCNTs)were obtained by functionalization of acid-purified singlewalled carbon nanotubes(O-SWCNTs)with biosurfactant soy protein isolate(SPI).SPI-O-SWCNTs and their performance were tested and characterized.Transmission electron microscopy(TEM)showed that SPI effectively improved the dispersibility of O-SWCNTs.X-ray photoelectron spectroscopy(XPS)and raman spectra analysis showed that the SPI adsorbed onto the surface of O-SWCNTs by physical action,resulting in a little increase of C atom confusion on the surface of O-SWCNTs and a decrease of electrochemical performance.The vitro drug release experiments and cytotoxicity tests showed that SPI-modified O-SWCNTs can improve the drug release effect and reduce the toxicity to cells.
作者
王寒
郭军
郭霞
贾剑红
李文凤
牛宝龙
Wang Han;Guo Jun;Guo Xia;Jia Jianhong;Li Wenfeng;Niu Baolong(Key Laboratory of Interface Science and Engineering in Advanced Materials, Ministry of Education, Taiyuan University of Technology, Taiyuan 030024;Breast Surgery of Shanxi Hospital,Taiyuan 030024;College of Materials Science and Engineering,Taiyuan University of Technology,Taiyuan 030024)
出处
《化工新型材料》
CAS
CSCD
北大核心
2019年第5期139-143,共5页
New Chemical Materials
基金
国家自然科学基金委青年科学基金(51303124)
山西省基础研究计划项目(2014021020-3)
山西省高等学校科技创新基金(153030141-S)
关键词
单壁碳纳米管
大豆分离蛋白
纳米复合材料
分散性
single-walled carbon nanotube
soy protein isolate
nanocomposite
dispersibility
